Weitz JI - Search Results

1

The Asp(272)-Glu(282) region of platelet glycoprotein Ibalpha interacts with the heparin-binding site of alpha-thrombin and protects the enzyme from the heparin-catalyzed inhibition by antithrombin III.

De Cristofaro R, De Candia E, Rutella S, Weitz JI. De Cristofaro R, et al. Among authors: weitz ji. J Biol Chem. 2000 Feb 11;275(6):3887-95. doi: 10.1074/jbc.275.6.3887. J Biol Chem. 2000. PMID: 10660541 Free article.

2

Exosites 1 and 2 are essential for protection of fibrin-bound thrombin from heparin-catalyzed inhibition by antithrombin and heparin cofactor II.

Becker DL, Fredenburgh JC, Stafford AR, Weitz JI. Becker DL, et al. Among authors: weitz ji. J Biol Chem. 1999 Mar 5;274(10):6226-33. doi: 10.1074/jbc.274.10.6226. J Biol Chem. 1999. PMID: 10037709 Free article.

3

Molecular basis for the susceptibility of fibrin-bound thrombin to inactivation by heparin cofactor ii in the presence of dermatan sulfate but not heparin.

Liaw PC, Becker DL, Stafford AR, Fredenburgh JC, Weitz JI. Liaw PC, et al. Among authors: weitz ji. J Biol Chem. 2001 Jun 15;276(24):20959-65. doi: 10.1074/jbc.M010584200. Epub 2001 Apr 9. J Biol Chem. 2001. PMID: 11294849 Free article.

4

Localization of the thrombin-binding domain on prothrombin fragment 2.

Liaw PC, Fredenburgh JC, Stafford AR, Tulinsky A, Austin RC, Weitz JI. Liaw PC, et al. Among authors: weitz ji. J Biol Chem. 1998 Apr 10;273(15):8932-9. doi: 10.1074/jbc.273.15.8932. J Biol Chem. 1998. PMID: 9535876 Free article.

5

Comparison of heparin- and dermatan sulfate-mediated catalysis of thrombin inactivation by heparin cofactor II.

Liaw PC, Austin RC, Fredenburgh JC, Stafford AR, Weitz JI. Liaw PC, et al. Among authors: weitz ji. J Biol Chem. 1999 Sep 24;274(39):27597-604. doi: 10.1074/jbc.274.39.27597. J Biol Chem. 1999. PMID: 10488098 Free article.

6

Evidence for allosteric linkage between exosites 1 and 2 of thrombin.

Fredenburgh JC, Stafford AR, Weitz JI. Fredenburgh JC, et al. Among authors: weitz ji. J Biol Chem. 1997 Oct 10;272(41):25493-9. doi: 10.1074/jbc.272.41.25493. J Biol Chem. 1997. PMID: 9325262 Free article.

7

Hypersulfated low molecular weight heparin with reduced affinity for antithrombin acts as an anticoagulant by inhibiting intrinsic tenase and prothrombinase.

Anderson JA, Fredenburgh JC, Stafford AR, Guo YS, Hirsh J, Ghazarossian V, Weitz JI. Anderson JA, et al. Among authors: weitz ji. J Biol Chem. 2001 Mar 30;276(13):9755-61. doi: 10.1074/jbc.M010048200. Epub 2000 Dec 27. J Biol Chem. 2001. PMID: 11134031 Free article.

8

Conformational changes in thrombin when complexed by serpins.

Fredenburgh JC, Stafford AR, Weitz JI. Fredenburgh JC, et al. Among authors: weitz ji. J Biol Chem. 2001 Nov 30;276(48):44828-34. doi: 10.1074/jbc.M108710200. Epub 2001 Oct 2. J Biol Chem. 2001. PMID: 11584020 Free article.

9

Characterization of the interactions of plasminogen and tissue and vampire bat plasminogen activators with fibrinogen, fibrin, and the complex of D-dimer noncovalently linked to fragment E.

Stewart RJ, Fredenburgh JC, Weitz JI. Stewart RJ, et al. Among authors: weitz ji. J Biol Chem. 1998 Jul 17;273(29):18292-9. doi: 10.1074/jbc.273.29.18292. J Biol Chem. 1998. PMID: 9660794 Free article.

10

Thrombin-activable fibrinolysis inhibitor attenuates (DD)E-mediated stimulation of plasminogen activation by reducing the affinity of (DD)E for tissue plasminogen activator. A potential mechanism for enhancing the fibrin specificity of tissue plasminogen activator.

Stewart RJ, Fredenburgh JC, Rischke JA, Bajzar L, Weitz JI. Stewart RJ, et al. Among authors: weitz ji. J Biol Chem. 2000 Nov 24;275(47):36612-20. doi: 10.1074/jbc.M005483200. J Biol Chem. 2000. PMID: 10970891 Free article.

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