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Fas/CD95/APO-1 can function as a death receptor for neuronal cells in vitro and in vivo and is upregulated following cerebral hypoxic-ischemic injury to the developing rat brain.
Felderhoff-Mueser U, Taylor DL, Greenwood K, Kozma M, Stibenz D, Joashi UC, Edwards AD, Mehmet H. Felderhoff-Mueser U, et al. Among authors: joashi uc. Brain Pathol. 2000 Jan;10(1):17-29. doi: 10.1111/j.1750-3639.2000.tb00239.x. Brain Pathol. 2000. PMID: 10668892 Free PMC article.
Branched chain amino acids induce apoptosis in neural cells without mitochondrial membrane depolarization or cytochrome c release: implications for neurological impairment associated with maple syrup urine disease.
Jouvet P, Rustin P, Taylor DL, Pocock JM, Felderhoff-Mueser U, Mazarakis ND, Sarraf C, Joashi U, Kozma M, Greenwood K, Edwards AD, Mehmet H. Jouvet P, et al. Mol Biol Cell. 2000 May;11(5):1919-32. doi: 10.1091/mbc.11.5.1919. Mol Biol Cell. 2000. PMID: 10793161 Free PMC article.