Lesk AM - Search Results

1

Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin.

Whisstock JC, Skinner R, Carrell RW, Lesk AM. Whisstock JC, et al. Among authors: lesk am. J Mol Biol. 2000 Feb 18;296(2):685-99. doi: 10.1006/jmbi.1999.3520. J Mol Biol. 2000. PMID: 10669617

2

Serpins in prokaryotes.

Irving JA, Steenbakkers PJ, Lesk AM, Op den Camp HJ, Pike RN, Whisstock JC. Irving JA, et al. Among authors: lesk am. Mol Biol Evol. 2002 Nov;19(11):1881-90. doi: 10.1093/oxfordjournals.molbev.a004012. Mol Biol Evol. 2002. PMID: 12411597

3

The 2.6 A structure of antithrombin indicates a conformational change at the heparin binding site.

Skinner R, Abrahams JP, Whisstock JC, Lesk AM, Carrell RW, Wardell MR. Skinner R, et al. Among authors: lesk am. J Mol Biol. 1997 Feb 28;266(3):601-9. doi: 10.1006/jmbi.1996.0798. J Mol Biol. 1997. PMID: 9067613

4

An atlas of serpin conformations.

Whisstock J, Skinner R, Lesk AM. Whisstock J, et al. Among authors: lesk am. Trends Biochem Sci. 1998 Feb;23(2):63-7. doi: 10.1016/s0968-0004(97)01172-9. Trends Biochem Sci. 1998. PMID: 9538691 Review.

5

Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin.

Whisstock JC, Skinner R, Carrell RW, Lesk AM. Whisstock JC, et al. Among authors: lesk am. J Mol Biol. 2000 Jan 21;295(3):651-65. doi: 10.1006/jmbi.1999.3375. J Mol Biol. 2000. PMID: 10623554

6

Conformational changes in serpins: II. The mechanism of activation of antithrombin by heparin.

Whisstock JC, Pike RN, Jin L, Skinner R, Pei XY, Carrell RW, Lesk AM. Whisstock JC, et al. Among authors: lesk am. J Mol Biol. 2000 Sep 1;301(5):1287-305. doi: 10.1006/jmbi.2000.3982. J Mol Biol. 2000. PMID: 10966821

7

Modeling of serpin-protease complexes: antithrombin-thrombin, alpha 1-antitrypsin (358Met-->Arg)-thrombin, alpha 1-antitrypsin (358Met-->Arg)-trypsin, and antitrypsin-elastase.

Whisstock J, Lesk AM, Carrell R. Whisstock J, et al. Among authors: lesk am. Proteins. 1996 Nov;26(3):288-303. doi: 10.1002/(SICI)1097-0134(199611)26:3<288::AID-PROT5>3.0.CO;2-A. Proteins. 1996. PMID: 8953650

8

Prediction of protein function from protein sequence and structure.

Whisstock JC, Lesk AM. Whisstock JC, et al. Among authors: lesk am. Q Rev Biophys. 2003 Aug;36(3):307-40. doi: 10.1017/s0033583503003901. Q Rev Biophys. 2003. PMID: 15029827 Review.

9

Preparative induction and characterization of L-antithrombin: a structural homologue of latent plasminogen activator inhibitor-1.

Wardell MR, Chang WS, Bruce D, Skinner R, Lesk AM, Carrell RW. Wardell MR, et al. Among authors: lesk am. Biochemistry. 1997 Oct 21;36(42):13133-42. doi: 10.1021/bi970664u. Biochemistry. 1997. PMID: 9335576

10

Serpins in the Caenorhabditis elegans genome.

Whisstock JC, Irving JA, Bottomley SP, Pike RN, Lesk AM. Whisstock JC, et al. Among authors: lesk am. Proteins. 1999 Jul 1;36(1):31-41. doi: 10.1002/(sici)1097-0134(19990701)36:1<31::aid-prot3>3.3.co;2-h. Proteins. 1999. PMID: 10373004

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