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A novel human immunodeficiency virus type 1 reverse transcriptase mutational pattern confers phenotypic lamivudine resistance in the absence of mutation 184V.
Hertogs K, Bloor S, De Vroey V, van Den Eynde C, Dehertogh P, van Cauwenberge A, Stürmer M, Alcorn T, Wegner S, van Houtte M, Miller V, Larder BA. Hertogs K, et al. Among authors: dehertogh p. Antimicrob Agents Chemother. 2000 Mar;44(3):568-73. doi: 10.1128/AAC.44.3.568-573.2000. Antimicrob Agents Chemother. 2000. PMID: 10681319 Free PMC article.
Resistance to antiretroviral therapy among patients in Uganda.
Weidle PJ, Kityo CM, Mugyenyi P, Downing R, Kebba A, Pieniazek D, Respess R, Hertogs K, De Vroey V, Dehertogh P, Bloor S, Larder B, Lackritz E. Weidle PJ, et al. Among authors: dehertogh p. J Acquir Immune Defic Syndr. 2001 Apr 15;26(5):495-500. doi: 10.1097/00126334-200104150-00017. J Acquir Immune Defic Syndr. 2001. PMID: 11391172
Drug-resistant reverse transcriptase genotyping and phenotyping of B and non-B subtypes (F and A) of human immunodeficiency virus type I found in Brazilian patients failing HAART.
Caride E, Brindeiro R, Hertogs K, Larder B, Dehertogh P, Machado E, de Sá CA, Eyer-Silva WA, Sion FS, Passioni LF, Menezes JA, Calazans AR, Tanuri A. Caride E, et al. Among authors: dehertogh p. Virology. 2000 Sep 15;275(1):107-15. doi: 10.1006/viro.2000.0487. Virology. 2000. PMID: 11017792 Free article.
Genotypic and phenotypic evidence of different drug-resistance mutation patterns between B and non-B subtype isolates of human immunodeficiency virus type 1 found in Brazilian patients failing HAART.
Caride E, Hertogs K, Larder B, Dehertogh P, Brindeiro R, Machado E, de Sá CA, Eyer-Silva WA, Sion FS, Passioni LF, Menezes JA, Calazans AR, Tanuri A. Caride E, et al. Among authors: dehertogh p. Virus Genes. 2001;23(2):193-202. doi: 10.1023/a:1011812810397. Virus Genes. 2001. PMID: 11724274
Antiviral activity and mode of action of TMC647078, a novel nucleoside inhibitor of the hepatitis C virus NS5B polymerase.
Berke JM, Vijgen L, Lachau-Durand S, Powdrill MH, Rawe S, Sjuvarsson E, Eriksson S, Götte M, Fransen E, Dehertogh P, Van den Eynde C, Leclercq L, Jonckers TH, Raboisson P, Nilsson M, Samuelsson B, Rosenquist Å, Fanning GC, Lin TI. Berke JM, et al. Among authors: dehertogh p. Antimicrob Agents Chemother. 2011 Aug;55(8):3812-20. doi: 10.1128/AAC.00214-11. Epub 2011 May 16. Antimicrob Agents Chemother. 2011. PMID: 21576430 Free PMC article.
In vitro resistance profile of the hepatitis C virus NS3/4A protease inhibitor TMC435.
Lenz O, Verbinnen T, Lin TI, Vijgen L, Cummings MD, Lindberg J, Berke JM, Dehertogh P, Fransen E, Scholliers A, Vermeiren K, Ivens T, Raboisson P, Edlund M, Storm S, Vrang L, de Kock H, Fanning GC, Simmen KA. Lenz O, et al. Among authors: dehertogh p. Antimicrob Agents Chemother. 2010 May;54(5):1878-87. doi: 10.1128/AAC.01452-09. Epub 2010 Feb 22. Antimicrob Agents Chemother. 2010. PMID: 20176898 Free PMC article.
Efficacy, tolerance, and pharmacokinetics of the combination of stavudine, nevirapine, nelfinavir, and saquinavir as salvage regimen after ritonavir or indinavir failure.
Casado JL, Dronda F, Hertogs K, Sabido R, Antela A, Martí-Belda P, Dehertogh P, Moreno S; NELSANE Study. Casado JL, et al. Among authors: dehertogh p. AIDS Res Hum Retroviruses. 2001 Jan 20;17(2):93-8. doi: 10.1089/08892220150217175. AIDS Res Hum Retroviruses. 2001. PMID: 11177388 Clinical Trial.
1,5-benzodiazepines, a novel class of hepatitis C virus polymerase nonnucleoside inhibitors.
Nyanguile O, Pauwels F, Van den Broeck W, Boutton CW, Quirynen L, Ivens T, van der Helm L, Vandercruyssen G, Mostmans W, Delouvroy F, Dehertogh P, Cummings MD, Bonfanti JF, Simmen KA, Raboisson P. Nyanguile O, et al. Among authors: dehertogh p. Antimicrob Agents Chemother. 2008 Dec;52(12):4420-31. doi: 10.1128/AAC.00669-08. Epub 2008 Oct 13. Antimicrob Agents Chemother. 2008. PMID: 18852280 Free PMC article.
24 results