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1-(2-Nitrophenyl)thiosemicarbazides: a novel class of potent, orally active non-peptide antagonist for the bradykinin B(2) receptor.
Dziadulewicz EK, Ritchie TJ, Hallett A, Snell CR, Ko SY, Wrigglesworth R, Hughes GA, Dunstan AR, Bloomfield GC, Drake GS, Brown MC, Lee W, Burgess GM, Davis C, Yaqoob M, Perkins MN, Campbell EA, Davis AJ, Rang HP. Dziadulewicz EK, et al. Among authors: drake gs. J Med Chem. 2000 Mar 9;43(5):769-71. doi: 10.1021/jm991155o. J Med Chem. 2000. PMID: 10715143 No abstract available.
Nonpeptide bradykinin B2 receptor antagonists: conversion of rodent-selective bradyzide analogues into potent, orally-active human bradykinin B2 receptor antagonists.
Dziadulewicz EK, Ritchie TJ, Hallett A, Snell CR, Davies JW, Wrigglesworth R, Dunstan AR, Bloomfield GC, Drake GS, McIntyre P, Brown MC, Burgess GM, Lee W, Davis C, Yaqoob M, Phagoo SB, Phillips E, Perkins MN, Campbell EA, Davis AJ, Rang HP. Dziadulewicz EK, et al. Among authors: drake gs. J Med Chem. 2002 May 23;45(11):2160-72. doi: 10.1021/jm0111088. J Med Chem. 2002. PMID: 12014954
Bradyzide, a potent non-peptide B(2) bradykinin receptor antagonist with long-lasting oral activity in animal models of inflammatory hyperalgesia.
Burgess GM, Perkins MN, Rang HP, Campbell EA, Brown MC, McIntyre P, Urban L, Dziadulewicz EK, Ritchie TJ, Hallett A, Snell CR, Wrigglesworth R, Lee W, Davis C, Phagoo SB, Davis AJ, Phillips E, Drake GS, Hughes GA, Dunstan A, Bloomfield GC. Burgess GM, et al. Among authors: drake gs. Br J Pharmacol. 2000 Jan;129(1):77-86. doi: 10.1038/sj.bjp.0703012. Br J Pharmacol. 2000. PMID: 10694205 Free PMC article.