Dafforn TR - Search Results

1

The effect of a reducing-end extension on pentasaccharide binding by antithrombin.

Belzar KJ, Dafforn TR, Petitou M, Carrell RW, Huntington JA. Belzar KJ, et al. Among authors: dafforn tr. J Biol Chem. 2000 Mar 24;275(12):8733-41. doi: 10.1074/jbc.275.12.8733. J Biol Chem. 2000. PMID: 10722716 Free article.

2

6-mer peptide selectively anneals to a pathogenic serpin conformation and blocks polymerization. Implications for the prevention of Z alpha(1)-antitrypsin-related cirrhosis.

Mahadeva R, Dafforn TR, Carrell RW, Lomas DA. Mahadeva R, et al. Among authors: dafforn tr. J Biol Chem. 2002 Mar 1;277(9):6771-4. doi: 10.1074/jbc.C100722200. Epub 2001 Dec 28. J Biol Chem. 2002. PMID: 11773044 Free article.

3

Polymerization of plasminogen activator inhibitor-1.

Zhou A, Faint R, Charlton P, Dafforn TR, Carrell RW, Lomas DA. Zhou A, et al. Among authors: dafforn tr. J Biol Chem. 2001 Mar 23;276(12):9115-22. doi: 10.1074/jbc.M010631200. Epub 2000 Dec 1. J Biol Chem. 2001. PMID: 11102455 Free article.

4

Antithrombins Wibble and Wobble (T85M/K): archetypal conformational diseases with in vivo latent-transition, thrombosis, and heparin activation.

Beauchamp NJ, Pike RN, Daly M, Butler L, Makris M, Dafforn TR, Zhou A, Fitton HL, Preston FE, Peake IR, Carrell RW. Beauchamp NJ, et al. Among authors: dafforn tr. Blood. 1998 Oct 15;92(8):2696-706. Blood. 1998. PMID: 9763552 Free article.

5

Inactive conformation of the serpin alpha(1)-antichymotrypsin indicates two-stage insertion of the reactive loop: implications for inhibitory function and conformational disease.

Gooptu B, Hazes B, Chang WS, Dafforn TR, Carrell RW, Read RJ, Lomas DA. Gooptu B, et al. Among authors: dafforn tr. Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):67-72. doi: 10.1073/pnas.97.1.67. Proc Natl Acad Sci U S A. 2000. PMID: 10618372 Free PMC article.

6

Introduction of a mutation in the shutter region of antithrombin (Phe77 --> Leu) increases affinity for heparin and decreases thermal stability.

Quinsey NS, Fitton HL, Coughlin P, Whisstock JC, Dafforn TR, Carrell RW, Bottomley SP, Pike RN. Quinsey NS, et al. Among authors: dafforn tr. Biochemistry. 2003 Sep 2;42(34):10169-73. doi: 10.1021/bi0349322. Biochemistry. 2003. PMID: 12939144

7

Murine serpin 2A is a redox-sensitive intracellular protein.

Morris EC, Dafforn TR, Forsyth SL, Missen MA, Horvath AJ, Hampson L, Hampson IN, Currie G, Carrell RW, Coughlin PB. Morris EC, et al. Among authors: dafforn tr. Biochem J. 2003 Apr 1;371(Pt 1):165-73. doi: 10.1042/BJ20021567. Biochem J. 2003. PMID: 12470299 Free PMC article.

8

Targeting a surface cavity of alpha 1-antitrypsin to prevent conformational disease.

Parfrey H, Mahadeva R, Ravenhill NA, Zhou A, Dafforn TR, Foreman RC, Lomas DA. Parfrey H, et al. Among authors: dafforn tr. J Biol Chem. 2003 Aug 29;278(35):33060-6. doi: 10.1074/jbc.M302646200. Epub 2003 Jun 13. J Biol Chem. 2003. PMID: 12807889 Free article.

9

The N-terminal segment of antithrombin acts as a steric gate for the binding of heparin.

Fitton HL, Skinner R, Dafforn TR, Jin L, Pike RN. Fitton HL, et al. Among authors: dafforn tr. Protein Sci. 1998 Mar;7(3):782-8. doi: 10.1002/pro.5560070328. Protein Sci. 1998. PMID: 9541411 Free PMC article.

10

The molecular interactions of heat shock protein 47 (Hsp47) and their implications for collagen biosynthesis.

Dafforn TR, Della M, Miller AD. Dafforn TR, et al. J Biol Chem. 2001 Dec 28;276(52):49310-9. doi: 10.1074/jbc.M108896200. Epub 2001 Oct 9. J Biol Chem. 2001. PMID: 11592970 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

143 results

Search Page

Filters