Wellington CL - Search Results

1

Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells.

Wellington CL, Singaraja R, Ellerby L, Savill J, Roy S, Leavitt B, Cattaneo E, Hackam A, Sharp A, Thornberry N, Nicholson DW, Bredesen DE, Hayden MR. Wellington CL, et al. J Biol Chem. 2000 Jun 30;275(26):19831-8. doi: 10.1074/jbc.M001475200. J Biol Chem. 2000. PMID: 10770929 Free article.

2

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain.

Kalchman MA, Koide HB, McCutcheon K, Graham RK, Nichol K, Nishiyama K, Kazemi-Esfarjani P, Lynn FC, Wellington C, Metzler M, Goldberg YP, Kanazawa I, Gietz RD, Hayden MR. Kalchman MA, et al. Nat Genet. 1997 May;16(1):44-53. doi: 10.1038/ng0597-44. Nat Genet. 1997. PMID: 9140394

3

Toward understanding the molecular pathology of Huntington's disease.

Wellington CL, Brinkman RR, O'Kusky JR, Hayden MR. Wellington CL, et al. Brain Pathol. 1997 Jul;7(3):979-1002. doi: 10.1111/j.1750-3639.1997.tb00897.x. Brain Pathol. 1997. PMID: 9217979 Free PMC article. Review.

4

Of molecular interactions, mice and mechanisms: new insights into Huntington's disease.

Wellington CL, Hayden MR. Wellington CL, et al. Curr Opin Neurol. 1997 Aug;10(4):291-8. doi: 10.1097/00019052-199708000-00003. Curr Opin Neurol. 1997. PMID: 9266152 Review.

5

Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates.

Martindale D, Hackam A, Wieczorek A, Ellerby L, Wellington C, McCutcheon K, Singaraja R, Kazemi-Esfarjani P, Devon R, Kim SU, Bredesen DE, Tufaro F, Hayden MR. Martindale D, et al. Nat Genet. 1998 Feb;18(2):150-4. doi: 10.1038/ng0298-150. Nat Genet. 1998. PMID: 9462744

6

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract.

Wellington CL, Ellerby LM, Hackam AS, Margolis RL, Trifiro MA, Singaraja R, McCutcheon K, Salvesen GS, Propp SS, Bromm M, Rowland KJ, Zhang T, Rasper D, Roy S, Thornberry N, Pinsky L, Kakizuka A, Ross CA, Nicholson DW, Bredesen DE, Hayden MR. Wellington CL, et al. J Biol Chem. 1998 Apr 10;273(15):9158-67. doi: 10.1074/jbc.273.15.9158. J Biol Chem. 1998. PMID: 9535906 Free article.

7

The influence of huntingtin protein size on nuclear localization and cellular toxicity.

Hackam AS, Singaraja R, Wellington CL, Metzler M, McCutcheon K, Zhang T, Kalchman M, Hayden MR. Hackam AS, et al. Among authors: wellington cl. J Cell Biol. 1998 Jun 1;141(5):1097-105. doi: 10.1083/jcb.141.5.1097. J Cell Biol. 1998. PMID: 9606203 Free PMC article.

8

The fatal attraction of polyglutamine-containing proteins.

Hackam AS, Wellington CL, Hayden MR. Hackam AS, et al. Among authors: wellington cl. Clin Genet. 1998 Apr;53(4):233-42. doi: 10.1111/j.1399-0004.1998.tb02687.x. Clin Genet. 1998. PMID: 9650759 Review. No abstract available.

9

Kennedy's disease: caspase cleavage of the androgen receptor is a crucial event in cytotoxicity.

Ellerby LM, Hackam AS, Propp SS, Ellerby HM, Rabizadeh S, Cashman NR, Trifiro MA, Pinsky L, Wellington CL, Salvesen GS, Hayden MR, Bredesen DE. Ellerby LM, et al. Among authors: wellington cl. J Neurochem. 1999 Jan;72(1):185-95. doi: 10.1046/j.1471-4159.1999.0720185.x. J Neurochem. 1999. PMID: 9886069 Free article.

10

Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity.

Ellerby LM, Andrusiak RL, Wellington CL, Hackam AS, Propp SS, Wood JD, Sharp AH, Margolis RL, Ross CA, Salvesen GS, Hayden MR, Bredesen DE. Ellerby LM, et al. Among authors: wellington cl. J Biol Chem. 1999 Mar 26;274(13):8730-6. doi: 10.1074/jbc.274.13.8730. J Biol Chem. 1999. PMID: 10085113 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

163 results

Search Page

Filters