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Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis.
Gelot C, Kovacs MT, Miron S, Mylne E, Haan A, Boeffard-Dosierre L, Ghouil R, Popova T, Dingli F, Loew D, Guirouilh-Barbat J, Del Nery E, Zinn-Justin S, Ceccaldi R. Gelot C, et al. Among authors: zinn justin s. Nature. 2023 Sep;621(7978):415-422. doi: 10.1038/s41586-023-06506-6. Epub 2023 Sep 6. Nature. 2023. PMID: 37674080 Free PMC article.
The BRCA2 R2645G variant increases DNA binding and induces hyper-recombination.
Alvaro-Aranda L, Petitalot A, Djeghmoum Y, Panigada D, Singh JK, Ehlén Å, Vugic D, Martin C, Miron S, Contreras-Perez A, Nhiri N, Boucherit V, Lafitte P, Dumoulin I, Quiles F, Rouleau E, Jacquet E, Feliubadaló L, Del Valle J, Sharan SK, Stoppa-Lyonnet D, Zinn-Justin S, Lázaro C, Caputo SM, Carreira A. Alvaro-Aranda L, et al. Among authors: zinn justin s. Nucleic Acids Res. 2024 Jul 8;52(12):6964-6976. doi: 10.1093/nar/gkad1222. Nucleic Acids Res. 2024. PMID: 38142462 Free PMC article.
105 results