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Synthesis and biological evaluation of xanthine derivatives with phenacyl group as tryptophan hydroxylase 1 (TPH1) inhibitors for obesity and fatty liver disease.
Yoon J, Choi WI, Parameswaran S, Lee GB, Choi BW, Kim P, Shin DS, Jeong HN, Lee SM, Oh CJ, Jeon JH, Lee IK, Bae MA, Kim H, Ahn JH. Yoon J, et al. Among authors: oh cj. Bioorg Med Chem Lett. 2023 Oct 1;94:129461. doi: 10.1016/j.bmcl.2023.129461. Epub 2023 Aug 29. Bioorg Med Chem Lett. 2023. PMID: 37652099
Inhibition of pyruvate dehydrogenase kinase 4 ameliorates kidney ischemia-reperfusion injury by reducing succinate accumulation during ischemia and preserving mitochondrial function during reperfusion.
Oh CJ, Kim MJ, Lee JM, Kim DH, Kim IY, Park S, Kim Y, Lee KB, Lee SH, Lim CW, Kim M, Lee JY, Pagire HS, Pagire SH, Bae MA, Chanda D, Thoudam T, Khang AR, Harris RA, Ahn JH, Jeon JH, Lee IK. Oh CJ, et al. Kidney Int. 2023 Oct;104(4):724-739. doi: 10.1016/j.kint.2023.06.022. Epub 2023 Jul 1. Kidney Int. 2023. PMID: 37399974
Upregulation of the ERRγ-VDAC1 axis underlies the molecular pathogenesis of pancreatitis.
Chanda D, Thoudam T, Sinam IS, Lim CW, Kim M, Wang J, Lee KM, Ma J, Saxena R, Choi J, Oh CJ, Lee H, Jeon YH, Cho SJ, Jung HY, Park KG, Choi HS, Suh JM, Auwerx J, Ji B, Liangpunsakul S, Jeon JH, Lee IK. Chanda D, et al. Among authors: oh cj. Proc Natl Acad Sci U S A. 2023 May 16;120(20):e2219644120. doi: 10.1073/pnas.2219644120. Epub 2023 May 8. Proc Natl Acad Sci U S A. 2023. PMID: 37155882 Free PMC article.
58 results