Elhalem E - Search Results

1

Design and synthesis of aryloxyethyl thiocyanate derivatives as potent inhibitors of Trypanosoma cruzi proliferation.

Szajnman SH, Yan W, Bailey BN, Docampo R, Elhalem E, Rodriguez JB. Szajnman SH, et al. Among authors: elhalem e. J Med Chem. 2000 May 4;43(9):1826-40. doi: 10.1021/jm9905007. J Med Chem. 2000. PMID: 10794699

2

Design, synthesis, and biological evaluation of aryloxyethyl thiocyanate derivatives against Trypanosoma cruzi.

Elhalem E, Bailey BN, Docampo R, Ujváry I, Szajnman SH, Rodriguez JB. Elhalem E, et al. J Med Chem. 2002 Aug 29;45(18):3984-99. doi: 10.1021/jm0201518. J Med Chem. 2002. PMID: 12190320

3

Design, Synthesis, and Characterization of Novel sn-1 Heterocyclic DAG-Lactones as PKC Activators.

Elhalem E, Bellomo A, Cooke M, Scravaglieri A, Pearce LV, Peach ML, Gandolfi Donadío L, Kazanietz MG, Comin MJ. Elhalem E, et al. J Med Chem. 2021 Aug 12;64(15):11418-11431. doi: 10.1021/acs.jmedchem.1c00739. Epub 2021 Jul 19. J Med Chem. 2021. PMID: 34279947

4

Structural determinants of efficacy at A3 adenosine receptors: modification of the ribose moiety.

Gao ZG, Jeong LS, Moon HR, Kim HO, Choi WJ, Shin DH, Elhalem E, Comin MJ, Melman N, Mamedova L, Gross AS, Rodriguez JB, Jacobson KA. Gao ZG, et al. Among authors: elhalem e. Biochem Pharmacol. 2004 Mar 1;67(5):893-901. doi: 10.1016/j.bcp.2003.10.006. Biochem Pharmacol. 2004. PMID: 15104242 Free PMC article.

5

Sulforaphane homologues: Enantiodivergent synthesis of both enantiomers, activation of the Nrf2 transcription factor and selective cytotoxic activity.

Elhalem E, Recio R, Werner S, Lieder F, Calderón-Montaño JM, López-Lázaro M, Fernández I, Khiar N. Elhalem E, et al. Eur J Med Chem. 2014 Nov 24;87:552-63. doi: 10.1016/j.ejmech.2014.09.052. Epub 2014 Sep 16. Eur J Med Chem. 2014. PMID: 25299679

6

Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP.

Elhalem E, Donadío LG, Zhou X, Lewin NE, Garcia LC, Lai CC, Kelley JA, Peach ML, Blumberg PM, Comin MJ. Elhalem E, et al. Bioorg Med Chem. 2017 Jun 15;25(12):2971-2980. doi: 10.1016/j.bmc.2017.03.022. Epub 2017 Mar 10. Bioorg Med Chem. 2017. PMID: 28392275 Free PMC article.

7

Studies on the diastereoselective oxidation of 1-thio-β-D-glucopyranosides: synthesis of the usually less favoured R(S) sulfoxide as a single diastereoisomer.

Moya-López JF, Elhalem E, Recio R, Álvarez E, Fernández I, Khiar N. Moya-López JF, et al. Among authors: elhalem e. Org Biomol Chem. 2015 Feb 14;13(6):1904-14. doi: 10.1039/c4ob02030h. Org Biomol Chem. 2015. PMID: 25519807 Free article.

8

NMR study on the stabilization and chiral discrimination of sulforaphane enantiomers and analogues by cyclodextrins.

Recio R, Elhalem E, Benito JM, Fernández I, Khiar N. Recio R, et al. Among authors: elhalem e. Carbohydr Polym. 2018 May 1;187:118-125. doi: 10.1016/j.carbpol.2017.12.022. Epub 2017 Dec 16. Carbohydr Polym. 2018. PMID: 29486836

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