Kirman CR - Search Results

1

Improving cancer dose-response characterization by using physiologically based pharmacokinetic modeling: an analysis of pooled data for acrylonitrile-induced brain tumors to assess cancer potency in the rat.

Kirman CR, Hays SM, Kedderis GL, Gargas ML, Strother DE. Kirman CR, et al. Risk Anal. 2000 Feb;20(1):135-51. doi: 10.1111/0272-4332.00013. Risk Anal. 2000. PMID: 10795346

2

Derivation of oral cancer slope factors for hexavalent chromium informed by pharmacokinetic models and in vivo genotoxicity data.

Thompson CM, Kirman C, Harris MA. Thompson CM, et al. Regul Toxicol Pharmacol. 2023 Dec;145:105521. doi: 10.1016/j.yrtph.2023.105521. Epub 2023 Oct 19. Regul Toxicol Pharmacol. 2023. PMID: 37863416 Free article.

3

Proposed occupational exposure limits for select ethylene glycol ethers using PBPK models and Monte Carlo simulations.

Sweeney LM, Tyler TR, Kirman CR, Corley RA, Reitz RH, Paustenbach DJ, Holson JF, Whorton MD, Thompson KM, Gargas ML. Sweeney LM, et al. Among authors: kirman cr. Toxicol Sci. 2001 Jul;62(1):124-39. doi: 10.1093/toxsci/62.1.124. Toxicol Sci. 2001. PMID: 11399800

4

A physiologically based pharmacokinetic model for acrylamide and its metabolite, glycidamide, in the rat.

Kirman CR, Gargas ML, Deskin R, Tonner-Navarro L, Andersen ME. Kirman CR, et al. J Toxicol Environ Health A. 2003 Feb 14;66(3):253-74. doi: 10.1080/15287390306368. J Toxicol Environ Health A. 2003. PMID: 12521671

5

Re: analysis of dioxin cancer threshold.

Aylward L, Kirman C, Cher D, Hays S. Aylward L, et al. Environ Health Perspect. 2003 Aug;111(10):A510. doi: 10.1289/ehp.111-a510a. Environ Health Perspect. 2003. PMID: 12896864 Free PMC article. No abstract available.

6

Assessing the dose-dependency of allometric scaling performance using physiologically based pharmacokinetic modeling.

Kirman CR, Sweeney LM, Meek ME, Gargas ML. Kirman CR, et al. Regul Toxicol Pharmacol. 2003 Dec;38(3):345-67. doi: 10.1016/j.yrtph.2003.07.004. Regul Toxicol Pharmacol. 2003. PMID: 14623485

7

Estimation of interindividual variation in oxidative metabolism of dichloromethane in human volunteers.

Sweeney LM, Kirman CR, Morgott DA, Gargas ML. Sweeney LM, et al. Among authors: kirman cr. Toxicol Lett. 2004 Dec 30;154(3):201-16. doi: 10.1016/j.toxlet.2004.08.002. Toxicol Lett. 2004. PMID: 15501612

8

Addressing nonlinearity in the exposure-response relationship for a genotoxic carcinogen: cancer potency estimates for ethylene oxide.

Kirman CR, Sweeney LM, Teta MJ, Sielken RL, Valdez-Flores C, Albertini RJ, Gargas ML. Kirman CR, et al. Risk Anal. 2004 Oct;24(5):1165-83. doi: 10.1111/j.0272-4332.2004.00517.x. Risk Anal. 2004. PMID: 15563286

9

Using physiologically-based pharmacokinetic modeling to address nonlinear kinetics and changes in rodent physiology and metabolism due to aging and adaptation in deriving reference values for propylene glycol methyl ether and propylene glycol methyl ether acetate.

Kirman CR, Sweeney LM, Corley R, Gargas ML. Kirman CR, et al. Risk Anal. 2005 Apr;25(2):271-84. doi: 10.1111/j.1539-6924.2005.00588.x. Risk Anal. 2005. PMID: 15876203

10

Cancer dose--response assessment for acrylonitrile based upon rodent brain tumor incidence: use of epidemiologic, mechanistic, and pharmacokinetic support for nonlinearity.

Kirman CR, Gargas ML, Marsh GM, Strother DE, Klaunig JE, Collins JJ, Deskin R. Kirman CR, et al. Regul Toxicol Pharmacol. 2005 Oct;43(1):85-103. doi: 10.1016/j.yrtph.2005.06.007. Regul Toxicol Pharmacol. 2005. PMID: 16099568

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