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Phenotypic assays and sequencing are less sensitive than point mutation assays for detection of resistance in mixed HIV-1 genotypic populations.
Van Laethem K, Van Vaerenbergh K, Schmit JC, Sprecher S, Hermans P, De Vroey V, Schuurman R, Harrer T, Witvrouw M, Van Wijngaerden E, Stuyver L, Van Ranst M, Desmyter J, De Clercq E, Vandamme AM. Van Laethem K, et al. Among authors: sprecher s. J Acquir Immune Defic Syndr. 1999 Oct 1;22(2):107-18. doi: 10.1097/00126334-199910010-00001. J Acquir Immune Defic Syndr. 1999. PMID: 10843523
Prevalence of genotypic resistance among antiretroviral drug-naive HIV-1-infected patients in Belgium.
Van Vaerenbergh K, Debaisieux L, De Cabooter N, Declercq C, Desmet K, Fransen K, Maes B, Marissens D, Miller K, Muyldermans G, Sprecher S, Stuyver L, Vaira D, Verhofstede C, Zissis G, Van Ranst M, De Clercq E, Desmyter J, Vandamme AM. Van Vaerenbergh K, et al. Among authors: sprecher s. Antivir Ther. 2001 Mar;6(1):63-70. Antivir Ther. 2001. PMID: 11417763
Presence of 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino-1",2"-oxath iole-2",2"-dioxide) (TSAO)-resistant virus strains in TSAO-inexperienced HIV patients.
Van Laethem K, Schmit JC, Pelemans H, Balzarini J, Witvrouw M, Pérez-Pérez MJ, Camarasa MJ, Esnouf RM, Aquaro S, Cenci A, Perno CF, Hermans P, Sprecher S, Ruiz L, Clotet B, Van Wijngaerden E, Van Ranst M, Desmyter J, De Clercq E, Vandamme AM. Van Laethem K, et al. Among authors: sprecher s. AIDS Res Hum Retroviruses. 2000 Jun 10;16(9):825-33. doi: 10.1089/08892220050042765. AIDS Res Hum Retroviruses. 2000. PMID: 10875608
Multiple drug resistance to nucleoside analogues and nonnucleoside reverse transcriptase inhibitors in an efficiently replicating human immunodeficiency virus type 1 patient strain.
Schmit JC, Cogniaux J, Hermans P, Van Vaeck C, Sprecher S, Van Remoortel B, Witvrouw M, Balzarini J, Desmyter J, De Clercq E, Vandamme AM. Schmit JC, et al. Among authors: sprecher s. J Infect Dis. 1996 Nov;174(5):962-8. doi: 10.1093/infdis/174.5.962. J Infect Dis. 1996. PMID: 8896496
Primary infection with zidovudine-resistant HIV.
Hermans P, Sprecher S, Clumeck N. Hermans P, et al. Among authors: sprecher s. N Engl J Med. 1993 Oct 7;329(15):1123; author reply 1124. doi: 10.1056/NEJM199310073291514. N Engl J Med. 1993. PMID: 8371738 No abstract available.
ADA, a potential anti-HIV drug.
Vandevelde M, Witvrouw M, Schmit JC, Sprecher S, De Clercq E, Tassignon JP. Vandevelde M, et al. Among authors: sprecher s. AIDS Res Hum Retroviruses. 1996 May 1;12(7):567-8. doi: 10.1089/aid.1996.12.567. AIDS Res Hum Retroviruses. 1996. PMID: 8743081 No abstract available.
139 results