Urae A - Search Results

1

Lack of differences in diclofenac (a substrate for CYP2C9) pharmacokinetics in healthy volunteers with respect to the single CYP2C9*3 allele.

Shimamoto J, Ieiri I, Urae A, Kimura M, Irie S, Kubota T, Chiba K, Ishizaki T, Otsubo K, Higuchi S. Shimamoto J, et al. Among authors: urae a. Eur J Clin Pharmacol. 2000 Apr;56(1):65-8. doi: 10.1007/s002280050722. Eur J Clin Pharmacol. 2000. PMID: 10853880

2

Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein.

Kurata Y, Ieiri I, Kimura M, Morita T, Irie S, Urae A, Ohdo S, Ohtani H, Sawada Y, Higuchi S, Otsubo K. Kurata Y, et al. Among authors: urae a. Clin Pharmacol Ther. 2002 Aug;72(2):209-19. doi: 10.1067/mcp.2002.126177. Clin Pharmacol Ther. 2002. PMID: 12189368

3

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics.

Nishizato Y, Ieiri I, Suzuki H, Kimura M, Kawabata K, Hirota T, Takane H, Irie S, Kusuhara H, Urasaki Y, Urae A, Higuchi S, Otsubo K, Sugiyama Y. Nishizato Y, et al. Among authors: urae a. Clin Pharmacol Ther. 2003 Jun;73(6):554-65. doi: 10.1016/S0009-9236(03)00060-2. Clin Pharmacol Ther. 2003. PMID: 12811365

4

Pharmacokinetics of omeprazole (a substrate of CYP2C19) and comparison with two mutant alleles, C gamma P2C19m1 in exon 5 and C gamma P2C19m2 in exon 4, in Japanese subjects.

Ieiri I, Kubota T, Urae A, Kimura M, Wada Y, Mamiya K, Yoshioka S, Irie S, Amamoto T, Nakamura K, Nakano S, Higuchi S. Ieiri I, et al. Among authors: urae a. Clin Pharmacol Ther. 1996 Jun;59(6):647-53. doi: 10.1016/S0009-9236(96)90004-1. Clin Pharmacol Ther. 1996. PMID: 8681489

5

Stereoselective 4'-hydroxylation of phenytoin: relationship to (S)-mephenytoin polymorphism in Japanese.

Ieiri I, Mamiya K, Urae A, Wada Y, Kimura M, Irie S, Amamoto T, Kubota T, Yoshioka S, Nakamura K, Nakano S, Tashiro N, Higuchi S. Ieiri I, et al. Among authors: urae a. Br J Clin Pharmacol. 1997 Apr;43(4):441-5. doi: 10.1046/j.1365-2125.1997.00572.x. Br J Clin Pharmacol. 1997. PMID: 9146858 Free PMC article. Clinical Trial.

6

Genetic polymorphism of cytochrome P450s, CYP2C19, and CYP2C9 in a Japanese population.

Kimura M, Ieiri I, Mamiya K, Urae A, Higuchi S. Kimura M, et al. Among authors: urae a. Ther Drug Monit. 1998 Jun;20(3):243-7. doi: 10.1097/00007691-199806000-00001. Ther Drug Monit. 1998. PMID: 9631918

7

Reliability of the omeprazole hydroxylation index for CYP2C19 phenotyping: possible effect of age, liver disease and length of therapy.

Kimura M, Ieiri I, Wada Y, Mamiya K, Urae A, Iimori E, Sakai T, Otsubo K, Higuchi S. Kimura M, et al. Among authors: urae a. Br J Clin Pharmacol. 1999 Jan;47(1):115-9. doi: 10.1046/j.1365-2125.1999.00858.x. Br J Clin Pharmacol. 1999. PMID: 10073749 Free PMC article. Clinical Trial.

8

Relationship between time after intake of grapefruit juice and the effect on pharmacokinetics and pharmacodynamics of nisoldipine in healthy subjects.

Takanaga H, Ohnishi A, Murakami H, Matsuo H, Higuchi S, Urae A, Irie S, Furuie H, Matsukuma K, Kimura M, Kawano K, Orii Y, Tanaka T, Sawada Y. Takanaga H, et al. Among authors: urae a. Clin Pharmacol Ther. 2000 Mar;67(3):201-14. doi: 10.1067/mcp.2000.104215. Clin Pharmacol Ther. 2000. PMID: 10741622 Clinical Trial.

9

Pharmacogenetic roles of CYP2C19 and CYP2B6 in the metabolism of R- and S-mephobarbital in humans.

Kobayashi K, Morita J, Chiba K, Wanibuchi A, Kimura M, Irie S, Urae A, Ishizaki T. Kobayashi K, et al. Among authors: urae a. Pharmacogenetics. 2004 Aug;14(8):549-56. doi: 10.1097/01.fpc.0000114764.78957.22. Pharmacogenetics. 2004. PMID: 15284537

10

Interaction magnitude, pharmacokinetics and pharmacodynamics of ticlopidine in relation to CYP2C19 genotypic status.

Ieiri I, Kimura M, Irie S, Urae A, Otsubo K, Ishizaki T. Ieiri I, et al. Among authors: urae a. Pharmacogenet Genomics. 2005 Dec;15(12):851-9. doi: 10.1097/01213011-200512000-00003. Pharmacogenet Genomics. 2005. PMID: 16272957

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