Ling YZ - Search Results

1

Anti-tumour effects and pharmacokinetic profile of 17-(5'-isoxazolyl)androsta-4,16-dien-3-one (L-39) in mice: an inhibitor of androgen synthesis.

Nnane IP, Long BJ, Ling YZ, Grigoryev DN, Brodie AM. Nnane IP, et al. Among authors: ling yz. Br J Cancer. 2000 Jul;83(1):74-82. doi: 10.1054/bjoc.2000.1136. Br J Cancer. 2000. PMID: 10883671 Free PMC article.

2

Growth inhibition of human prostate cells in vitro by novel inhibitors of androgen synthesis.

Klus GT, Nakamura J, Li JS, Ling YZ, Son C, Kemppainen JA, Wilson EM, Brodie AM. Klus GT, et al. Among authors: ling yz. Cancer Res. 1996 Nov 1;56(21):4956-64. Cancer Res. 1996. PMID: 8895750

3

Effects of some novel inhibitors of C17,20-lyase and 5alpha-reductase in vitro and in vivo and their potential role in the treatment of prostate cancer.

Nnane IP, Kato K, Liu Y, Lu Q, Wang X, Ling YZ, Brodie A. Nnane IP, et al. Among authors: ling yz. Cancer Res. 1998 Sep 1;58(17):3826-32. Cancer Res. 1998. PMID: 9731491

4

Synthesis and in vitro activity of some epimeric 20 alpha-hydroxy, 20-oxime and aziridine pregnene derivatives as inhibitors of human 17 alpha-hydroxylase/C17,20-lyase and 5 alpha-reductase.

Ling YZ, Li JS, Kato K, Liu Y, Wang X, Klus GT, Marat K, Nnane IP, Brodie AM. Ling YZ, et al. Bioorg Med Chem. 1998 Oct;6(10):1683-93. doi: 10.1016/s0968-0896(98)00110-2. Bioorg Med Chem. 1998. PMID: 9839000

5

Cytochrome P450c17-expressing Escherichia coli as a first-step screening system for 17alpha-hydroxylase-C17,20-lyase inhibitors.

Grigoryev DN, Kato K, Njar VC, Long BJ, Ling YZ, Wang X, Mohler J, Brodie AM. Grigoryev DN, et al. Among authors: ling yz. Anal Biochem. 1999 Feb 15;267(2):319-30. doi: 10.1006/abio.1998.2993. Anal Biochem. 1999. PMID: 10036137

6

Inhibition of androgen synthesis in human testicular and prostatic microsomes and in male rats by novel steroidal compounds.

Nnane IP, Kato K, Liu Y, Long BJ, Lu Q, Wang X, Ling YZ, Brodie A. Nnane IP, et al. Among authors: ling yz. Endocrinology. 1999 Jun;140(6):2891-7. doi: 10.1210/endo.140.6.6832. Endocrinology. 1999. PMID: 10342882

7

Antiandrogenic effects of novel androgen synthesis inhibitors on hormone-dependent prostate cancer.

Long BJ, Grigoryev DN, Nnane IP, Liu Y, Ling YZ, Brodie AM. Long BJ, et al. Among authors: ling yz. Cancer Res. 2000 Dec 1;60(23):6630-40. Cancer Res. 2000. PMID: 11118046

8

17-Imidazolyl, pyrazolyl, and isoxazolyl androstene derivatives. Novel steroidal inhibitors of human cytochrome C17,20-lyase (P450(17 alpha).

Ling YZ, Li JS, Liu Y, Kato K, Klus GT, Brodie A. Ling YZ, et al. J Med Chem. 1997 Sep 26;40(20):3297-304. doi: 10.1021/jm970337k. J Med Chem. 1997. PMID: 9379450

9

Novel P450(17alpha) inhibitors: 17-(2'-oxazolyl)- and 17-(2'-thiazolyl)-androstene derivatives.

Zhu N, Ling Y, Lei X, Handratta V, Brodie AM. Zhu N, et al. Steroids. 2003 Sep;68(7-8):603-11. doi: 10.1016/s0039-128x(03)00082-5. Steroids. 2003. PMID: 12957665

10

A versatile synthesis of 17-heteroaryl androstenes via palladium-mediated Suzuki cross-coupling with heteroaryl boronic acids.

Chao J, Ling Y, Liu X, Luo X, Brodie AM. Chao J, et al. Steroids. 2006 Jul;71(7):585-90. doi: 10.1016/j.steroids.2006.02.004. Epub 2006 Mar 29. Steroids. 2006. PMID: 16566953

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