Havlícek L - Search Results

1

Docking-based development of purine-like inhibitors of cyclin-dependent kinase-2.

Otyepka M, Krystof V, Havlícek L, Siglerová V, Strnad M, Koca J. Otyepka M, et al. Among authors: havlicek l. J Med Chem. 2000 Jun 29;43(13):2506-13. doi: 10.1021/jm990506w. J Med Chem. 2000. PMID: 10891109

2

Inhibition of cyclin-dependent kinases by purine analogues.

Veselý J, Havlicek L, Strnad M, Blow JJ, Donella-Deana A, Pinna L, Letham DS, Kato J, Detivaud L, Leclerc S, et al. Veselý J, et al. Among authors: havlicek l. Eur J Biochem. 1994 Sep 1;224(2):771-86. doi: 10.1111/j.1432-1033.1994.00771.x. Eur J Biochem. 1994. PMID: 7925396 Free article.

3

Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine.

De Azevedo WF, Leclerc S, Meijer L, Havlicek L, Strnad M, Kim SH. De Azevedo WF, et al. Among authors: havlicek l. Eur J Biochem. 1997 Jan 15;243(1-2):518-26. doi: 10.1111/j.1432-1033.1997.0518a.x. Eur J Biochem. 1997. PMID: 9030780 Free article.

4

Cytokinin-derived cyclin-dependent kinase inhibitors: synthesis and cdc2 inhibitory activity of olomoucine and related compounds.

Havlícek L, Hanus J, Veselý J, Leclerc S, Meijer L, Shaw G, Strnad M. Havlícek L, et al. J Med Chem. 1997 Feb 14;40(4):408-12. doi: 10.1021/jm960666x. J Med Chem. 1997. PMID: 9046330

5

In vivo metabolism of 2,6,9-trisubstituted purine-derived cyclin-dependent kinase inhibitor bohemine in mice: glucosidation as the principal metabolic route.

Chmela Z, Veselý J, Lemr K, Rypka M, Hanus J, Havlícek L, Krystof V, Michnová L, Fuksová K, Lukes J. Chmela Z, et al. Among authors: havlicek l. Drug Metab Dispos. 2001 Mar;29(3):326-34. Drug Metab Dispos. 2001. PMID: 11181503

6

Antiproliferative effect of plant cytokinin analogues with an inhibitory activity on cyclin-dependent kinases.

Vermeulen K, Strnad M, Krystof V, Havlícek L, Van der Aa A, Lenjou M, Nijs G, Rodrigus I, Stockman B, van Onckelen H, Van Bockstaele DR, Berneman ZN. Vermeulen K, et al. Among authors: havlicek l. Leukemia. 2002 Mar;16(3):299-305. doi: 10.1038/sj.leu.2402378. Leukemia. 2002. PMID: 11896531

7

Plant cytokinin analogues with inhibitory activity on cyclin-dependent kinases exert their antiproliferative effect through induction of apoptosis initiated by the mitochondrial pathway: determination by a multiparametric flow cytometric analysis.

Vermeulen K, Strnad M, Havlícek L, Van Onckelen H, Lenjou M, Nijs G, Van Bockstaele DR, Berneman ZN. Vermeulen K, et al. Among authors: havlicek l. Exp Hematol. 2002 Oct;30(10):1107-14. doi: 10.1016/s0301-472x(02)00894-9. Exp Hematol. 2002. PMID: 12384140 Free article.

8

Synthesis and biological activity of olomoucine II.

Krystof V, Lenobel R, Havlícek L, Kuzma M, Strnad M. Krystof V, et al. Among authors: havlicek l. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3283-6. doi: 10.1016/s0960-894x(02)00693-5. Bioorg Med Chem Lett. 2002. PMID: 12392733

9

In vitro biotransformation of 2,6,9-trisubstituted purine-derived cyclin-dependent kinase inhibitor bohemine by mouse liver microsomes.

Rypka M, Veselý J, Chmela Z, Riegrová D, Cervenková K, Havlícek L, Lemr K, Hanus J, Cerný B, Lukes J, Michalíková K. Rypka M, et al. Among authors: havlicek l. Xenobiotica. 2002 Nov;32(11):1017-31. doi: 10.1080/0049825021000012600. Xenobiotica. 2002. PMID: 12487731

10

In vitro glycosidation potential towards olomoucine-type cyclin-dependent kinase inhibitors in rodent and primate microsomes.

Cervenková K, Belejová M, Chmela Z, Rypka M, Riegrová D, Michnová K, Michalíková K, Súrová I, Brejcha A, Hanus J, Cerný B, Fuksová K, Havlícek L, Veselý J. Cervenková K, et al. Among authors: havlicek l. Physiol Res. 2003;52(4):467-74. Physiol Res. 2003. PMID: 12899660 Free article.

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