Huddler D - Search Results

1

A distinctive role for the Yersinia protein kinase: actin binding, kinase activation, and cytoskeleton disruption.

Juris SJ, Rudolph AE, Huddler D, Orth K, Dixon JE. Juris SJ, et al. Among authors: huddler d. Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9431-6. doi: 10.1073/pnas.170281997. Proc Natl Acad Sci U S A. 2000. PMID: 10920208 Free PMC article.

2

Drosophila Ack targets its substrate, the sorting nexin DSH3PX1, to a protein complex involved in axonal guidance.

Worby CA, Simonson-Leff N, Clemens JC, Huddler D Jr, Muda M, Dixon JE. Worby CA, et al. Among authors: huddler d jr. J Biol Chem. 2002 Mar 15;277(11):9422-8. doi: 10.1074/jbc.M110172200. Epub 2001 Dec 28. J Biol Chem. 2002. PMID: 11773052 Free article.

3

Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase.

Evans JC, Huddler DP, Hilgers MT, Romanchuk G, Matthews RG, Ludwig ML. Evans JC, et al. Among authors: huddler dp. Proc Natl Acad Sci U S A. 2004 Mar 16;101(11):3729-36. doi: 10.1073/pnas.0308082100. Epub 2004 Jan 29. Proc Natl Acad Sci U S A. 2004. PMID: 14752199 Free PMC article.

4

Domain alternation switches B(12)-dependent methionine synthase to the activation conformation.

Bandarian V, Pattridge KA, Lennon BW, Huddler DP, Matthews RG, Ludwig ML. Bandarian V, et al. Among authors: huddler dp. Nat Struct Biol. 2002 Jan;9(1):53-6. doi: 10.1038/nsb738. Nat Struct Biol. 2002. PMID: 11731805

5

Betaine-homocysteine methyltransferase: zinc in a distorted barrel.

Evans JC, Huddler DP, Jiracek J, Castro C, Millian NS, Garrow TA, Ludwig ML. Evans JC, et al. Among authors: huddler dp. Structure. 2002 Sep;10(9):1159-71. doi: 10.1016/s0969-2126(02)00796-7. Structure. 2002. PMID: 12220488 Free article.

6

The crystal structure of a major allergen from plants.

Thorn KS, Christensen HE, Shigeta R, Huddler D, Shalaby L, Lindberg U, Chua NH, Schutt CE. Thorn KS, et al. Among authors: huddler d. Structure. 1997 Jan 15;5(1):19-32. doi: 10.1016/s0969-2126(97)00163-9. Structure. 1997. PMID: 9016723 Free article.

7

Synthesis and biological evaluation of thiazolidine-2-one 1,1-dioxide as inhibitors of Escherichia coli beta-ketoacyl-ACP-synthase III (FabH).

Alhamadsheh MM, Waters NC, Huddler DP, Kreishman-Deitrick M, Florova G, Reynolds KA. Alhamadsheh MM, et al. Among authors: huddler dp. Bioorg Med Chem Lett. 2007 Feb 15;17(4):879-83. doi: 10.1016/j.bmcl.2006.11.067. Epub 2006 Dec 1. Bioorg Med Chem Lett. 2007. PMID: 17189694

8

Targeting the fatty acid biosynthesis enzyme, beta-ketoacyl-acyl carrier protein synthase III (PfKASIII), in the identification of novel antimalarial agents.

Lee PJ, Bhonsle JB, Gaona HW, Huddler DP, Heady TN, Kreishman-Deitrick M, Bhattacharjee A, McCalmont WF, Gerena L, Lopez-Sanchez M, Roncal NE, Hudson TH, Johnson JD, Prigge ST, Waters NC. Lee PJ, et al. Among authors: huddler dp. J Med Chem. 2009 Feb 26;52(4):952-63. doi: 10.1021/jm8008103. J Med Chem. 2009. PMID: 19191586 Free PMC article.

9

Application of 3D-QSAR for identification of descriptors defining bioactivity of antimicrobial peptides.

Bhonsle JB, Venugopal D, Huddler DP, Magill AJ, Hicks RP. Bhonsle JB, et al. Among authors: huddler dp. J Med Chem. 2007 Dec 27;50(26):6545-53. doi: 10.1021/jm070884y. Epub 2007 Dec 7. J Med Chem. 2007. PMID: 18062663

10

Identification of catalytic cysteine, histidine, and lysine residues in Escherichia coli homoserine transsuccinylase.

Ziegler K, Noble SM, Mutumanje E, Bishop B, Huddler DP, Born TL. Ziegler K, et al. Among authors: huddler dp. Biochemistry. 2007 Mar 13;46(10):2674-83. doi: 10.1021/bi0620252. Epub 2007 Feb 16. Biochemistry. 2007. PMID: 17302437

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