Schlessinger J - Search Results

1

SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors.

Laird AD, Vajkoczy P, Shawver LK, Thurnher A, Liang C, Mohammadi M, Schlessinger J, Ullrich A, Hubbard SR, Blake RA, Fong TA, Strawn LM, Sun L, Tang C, Hawtin R, Tang F, Shenoy N, Hirth KP, McMahon G, Cherrington. Laird AD, et al. Among authors: schlessinger j. Cancer Res. 2000 Aug 1;60(15):4152-60. Cancer Res. 2000. PMID: 10945623

2

Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells.

Hudziak RM, Schlessinger J, Ullrich A. Hudziak RM, et al. Among authors: schlessinger j. Proc Natl Acad Sci U S A. 1987 Oct;84(20):7159-63. doi: 10.1073/pnas.84.20.7159. Proc Natl Acad Sci U S A. 1987. PMID: 2890160 Free PMC article.

3

Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism.

Mohammadi M, Schlessinger J, Hubbard SR. Mohammadi M, et al. Among authors: schlessinger j. Cell. 1996 Aug 23;86(4):577-87. doi: 10.1016/s0092-8674(00)80131-2. Cell. 1996. PMID: 8752212 Free article.

4

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors.

Mohammadi M, McMahon G, Sun L, Tang C, Hirth P, Yeh BK, Hubbard SR, Schlessinger J. Mohammadi M, et al. Among authors: schlessinger j. Science. 1997 May 9;276(5314):955-60. doi: 10.1126/science.276.5314.955. Science. 1997. PMID: 9139660

5

Differential signalling potential of insulin- and IGF-1-receptor cytoplasmic domains.

Lammers R, Gray A, Schlessinger J, Ullrich A. Lammers R, et al. Among authors: schlessinger j. EMBO J. 1989 May;8(5):1369-75. doi: 10.1002/j.1460-2075.1989.tb03517.x. EMBO J. 1989. PMID: 2548842 Free PMC article.

6

Autoregulatory mechanisms in protein-tyrosine kinases.

Hubbard SR, Mohammadi M, Schlessinger J. Hubbard SR, et al. Among authors: schlessinger j. J Biol Chem. 1998 May 15;273(20):11987-90. doi: 10.1074/jbc.273.20.11987. J Biol Chem. 1998. PMID: 9575136 Free article. Review. No abstract available.

7

HER2 cytoplasmic domain generates normal mitogenic and transforming signals in a chimeric receptor.

Lee J, Dull TJ, Lax I, Schlessinger J, Ullrich A. Lee J, et al. Among authors: schlessinger j. EMBO J. 1989 Jan;8(1):167-73. doi: 10.1002/j.1460-2075.1989.tb03361.x. EMBO J. 1989. PMID: 2565808 Free PMC article.

8

Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain.

Mohammadi M, Froum S, Hamby JM, Schroeder MC, Panek RL, Lu GH, Eliseenkova AV, Green D, Schlessinger J, Hubbard SR. Mohammadi M, et al. Among authors: schlessinger j. EMBO J. 1998 Oct 15;17(20):5896-904. doi: 10.1093/emboj/17.20.5896. EMBO J. 1998. PMID: 9774334 Free PMC article.

9

Structural basis for FGF receptor dimerization and activation.

Plotnikov AN, Schlessinger J, Hubbard SR, Mohammadi M. Plotnikov AN, et al. Among authors: schlessinger j. Cell. 1999 Sep 3;98(5):641-50. doi: 10.1016/s0092-8674(00)80051-3. Cell. 1999. PMID: 10490103 Free article.

10

Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity.

Plotnikov AN, Hubbard SR, Schlessinger J, Mohammadi M. Plotnikov AN, et al. Among authors: schlessinger j. Cell. 2000 May 12;101(4):413-24. doi: 10.1016/s0092-8674(00)80851-x. Cell. 2000. PMID: 10830168 Free article.

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