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Page 1
High-resolution LC/MS for analysis of minor components in complex mixtures: negative ion ESI for identification of impurities and degradation products of a novel oligosaccharide antibiotic.
Shipkova PA, Heimark L, Bartner PL, Chen G, Pramanik BN, Ganguly AK, Cody RB, Kusai A. Shipkova PA, et al. Among authors: heimark l. J Mass Spectrom. 2000 Nov;35(11):1252-8. doi: 10.1002/1096-9888(200011)35:11<1252::AID-JMS56>3.0.CO;2-J. J Mass Spectrom. 2000. PMID: 11114082
Ras oncoprotein inhibitors: the discovery of potent, ras nucleotide exchange inhibitors and the structural determination of a drug-protein complex.
Taveras AG, Remiszewski SW, Doll RJ, Cesarz D, Huang EC, Kirschmeier P, Pramanik BN, Snow ME, Wang YS, del Rosario JD, Vibulbhan B, Bauer BB, Brown JE, Carr D, Catino J, Evans CA, Girijavallabhan V, Heimark L, James L, Liberles S, Nash C, Perkins L, Senior MM, Tsarbopoulos A, Webber SE, et al. Taveras AG, et al. Among authors: heimark l. Bioorg Med Chem. 1997 Jan;5(1):125-33. doi: 10.1016/s0968-0896(96)00202-7. Bioorg Med Chem. 1997. PMID: 9043664
Detection and structural characterization of ras oncoprotein-inhibitors complexes by electrospray mass spectrometry.
Ganguly AK, Pramanik BN, Huang EC, Liberles S, Heimark L, Liu YH, Tsarbopoulos A, Doll RJ, Taveras AG, Remiszewski S, Snow ME, Wang YS, Vibulbhan B, Cesarz D, Brown JE, del Rosario J, James L, Kirschmeier P, Girijavallabhan V. Ganguly AK, et al. Among authors: heimark l. Bioorg Med Chem. 1997 May;5(5):817-20. doi: 10.1016/s0968-0896(97)00021-7. Bioorg Med Chem. 1997. PMID: 9208093
Posaconazole (Noxafil, SCH 56592), a new azole antifungal drug, was a discovery based on the isolation and mass spectral characterization of a circulating metabolite of an earlier lead (SCH 51048).
Nomeir AA, Pramanik BN, Heimark L, Bennett F, Veals J, Bartner P, Hilbert M, Saksena A, McNamara P, Girijavallabhan V, Ganguly AK, Lovey R, Pike R, Wang H, Liu YT, Kumari P, Korfmacher W, Lin CC, Cacciapuoti A, Loebenberg D, Hare R, Miller G, Pickett C. Nomeir AA, et al. Among authors: heimark l. J Mass Spectrom. 2008 Apr;43(4):509-17. doi: 10.1002/jms.1341. J Mass Spectrom. 2008. PMID: 18059003
Identification of pharmacokinetically stable 3, 10-dibromo-8-chlorobenzocycloheptapyridine farnesyl protein transferase inhibitors with potent enzyme and cellular activities.
Taveras AG, Deskus J, Chao J, Vaccaro CJ, Njoroge FG, Vibulbhan B, Pinto P, Remiszewski S, del Rosario J, Doll RJ, Alvarez C, Lalwani T, Mallams AK, Rossman RR, Afonso A, Girijavallabhan VM, Ganguly AK, Pramanik B, Heimark L, Bishop WR, Wang L, Kirschmeier P, James L, Carr D, Liu M, et al. Taveras AG, et al. Among authors: heimark l. J Med Chem. 1999 Jul 15;42(14):2651-61. doi: 10.1021/jm990059k. J Med Chem. 1999. PMID: 10411485
Microwave enhanced Akabori reaction for peptide analysis.
Bose AK, Ing YH, Lavlinskaia N, Sareen C, Pramanik BN, Bartner PL, Liu YH, Heimark L. Bose AK, et al. Among authors: heimark l. J Am Soc Mass Spectrom. 2002 Jul;13(7):839-50. doi: 10.1016/S1044-0305(02)00387-2. J Am Soc Mass Spectrom. 2002. PMID: 12148808 Free article.
Isolation, structural determination, synthesis and quantitative determination of impurities in Intron-A, leached from a silicone tubing.
Chan TM, Pramanik B, Aslanian R, Gullo V, Patel M, Cronin B, Boyce C, McCormick K, Berlin M, Zhu X, Buevich A, Heimark L, Bartner P, Chen G, Pu H, Hegde V. Chan TM, et al. Among authors: heimark l. J Pharm Biomed Anal. 2009 Feb 20;49(2):327-32. doi: 10.1016/j.jpba.2008.11.038. Epub 2008 Dec 6. J Pharm Biomed Anal. 2009. PMID: 19150187
26 results