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Neurosteroid analogues. 8. Structure-activity studies of N-acylated 17a-aza-D-homosteroid analogues of the anesthetic steroids (3alpha, 5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.
Covey DF, Han M, Kumar AS, de La Cruz MA, Meadows ES, Hu Y, Tonnies A, Nathan D, Coleman M, Benz A, Evers AS, Zorumski CF, Mennerick S. Covey DF, et al. Among authors: evers as. J Med Chem. 2000 Aug 24;43(17):3201-4. doi: 10.1021/jm0002477. J Med Chem. 2000. PMID: 10966737 No abstract available.
Neuroactive steroid interactions with voltage-dependent anion channels: lack of relationship to GABA(A) receptor modulation and anesthesia.
Darbandi-Tonkabon R, Manion BD, Hastings WR, Craigen WJ, Akk G, Bracamontes JR, He Y, Sheiko TV, Steinbach JH, Mennerick SJ, Covey DF, Evers AS. Darbandi-Tonkabon R, et al. Among authors: evers as. J Pharmacol Exp Ther. 2004 Feb;308(2):502-11. doi: 10.1124/jpet.103.058123. Epub 2003 Oct 30. J Pharmacol Exp Ther. 2004. PMID: 14593090
Neurosteroid analogues. 9. Conformationally constrained pregnanes: structure-activity studies of 13,24-cyclo-18,21-dinorcholane analogues of the GABA modulatory and anesthetic steroids (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.
Jiang X, Manion BD, Benz A, Rath NP, Evers AS, Zorumski CF, Mennerick S, Covey DF. Jiang X, et al. Among authors: evers as. J Med Chem. 2003 Dec 4;46(25):5334-48. doi: 10.1021/jm030302m. J Med Chem. 2003. PMID: 14640542
138 results