Xu Y - Search Results

1

Enhanced mitochondrial DNA repair and cellular survival after oxidative stress by targeting the human 8-oxoguanine glycosylase repair enzyme to mitochondria.

Dobson AW, Xu Y, Kelley MR, LeDoux SP, Wilson GL. Dobson AW, et al. Among authors: xu y. J Biol Chem. 2000 Dec 1;275(48):37518-23. doi: 10.1074/jbc.M000831200. J Biol Chem. 2000. PMID: 10982789 Free article.

2

Yeast apurinic/apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress.

Ho R, Rachek LI, Xu Y, Kelley MR, LeDoux SP, Wilson GL. Ho R, et al. Among authors: xu y. J Neurochem. 2007 Jul;102(1):13-24. doi: 10.1111/j.1471-4159.2007.04490.x. Epub 2007 May 15. J Neurochem. 2007. PMID: 17506861 Free PMC article.

3

Creation of a fully functional human chimeric DNA repair protein. Combining O6-methylguanine DNA methyltransferase (MGMT) and AP endonuclease (APE/redox effector factor 1 (Ref 1)) DNA repair proteins.

Hansen WK, Deutsch WA, Yacoub A, Xu Y, Williams DA, Kelley MR. Hansen WK, et al. Among authors: xu y. J Biol Chem. 1998 Jan 9;273(2):756-62. doi: 10.1074/jbc.273.2.756. J Biol Chem. 1998. PMID: 9422728 Free article.

4

Protection of mammalian cells against chemotherapeutic agents thiotepa, 1,3-N,N'-bis(2-chloroethyl)-N-nitrosourea, and mafosfamide using the DNA base excision repair genes Fpg and alpha-hOgg1: implications for protective gene therapy applications.

Xu Y, Hansen WK, Rosenquist TA, Williams DA, Limp-Foster M, Kelley MR. Xu Y, et al. J Pharmacol Exp Ther. 2001 Mar;296(3):825-31. J Pharmacol Exp Ther. 2001. PMID: 11181913

5

Conversion of the bifunctional 8-oxoguanine/beta-delta apurinic/apyrimidinic DNA repair activities of Drosophila ribosomal protein S3 into the human S3 monofunctional beta-elimination catalyst through a single amino acid change.

Hegde V, Kelley MR, Xu Y, Mian IS, Deutsch WA. Hegde V, et al. Among authors: xu y. J Biol Chem. 2001 Jul 20;276(29):27591-6. doi: 10.1074/jbc.M101213200. Epub 2001 May 15. J Biol Chem. 2001. PMID: 11353770 Free article.

6

A novel fluorometric oligonucleotide assay to measure O( 6)-methylguanine DNA methyltransferase, methylpurine DNA glycosylase, 8-oxoguanine DNA glycosylase and abasic endonuclease activities: DNA repair status in human breast carcinoma cells overexpressing methylpurine DNA glycosylase.

Kreklau EL, Limp-Foster M, Liu N, Xu Y, Kelley MR, Erickson LC. Kreklau EL, et al. Among authors: xu y. Nucleic Acids Res. 2001 Jun 15;29(12):2558-66. doi: 10.1093/nar/29.12.2558. Nucleic Acids Res. 2001. PMID: 11410664 Free PMC article.

7

Retrovirus-mediated expression of the base excision repair proteins, formamidopyrimidine DNA glycosylase or human oxoguanine DNA glycosylase, protects hematopoietic cells from N,N',N"-triethylenethiophosphoramide (thioTEPA)-induced toxicity in vitro and in vivo.

Kobune M, Xu Y, Baum C, Kelley MR, Williams DA. Kobune M, et al. Among authors: xu y. Cancer Res. 2001 Jul 1;61(13):5116-25. Cancer Res. 2001. PMID: 11431349

8

Protection of human lung cells against hyperoxia using the DNA base excision repair genes hOgg1 and Fpg.

Wu M, He YH, Kobune M, Xu Y, Kelley MR, Martin WJ 2nd. Wu M, et al. Among authors: xu y. Am J Respir Crit Care Med. 2002 Jul 15;166(2):192-9. doi: 10.1164/rccm.200112-130OC. Am J Respir Crit Care Med. 2002. PMID: 12119232

9

Protection of pulmonary epithelial cells from oxidative stress by hMYH adenine glycosylase.

Kremer TM, Rinne ML, Xu Y, Chen XM, Kelley MR. Kremer TM, et al. Among authors: xu y. Respir Res. 2004 Sep 27;5(1):16. doi: 10.1186/1465-9921-5-16. Respir Res. 2004. PMID: 15450125 Free PMC article.

10

The Drosophila S3 multifunctional DNA repair/ribosomal protein protects Fanconi anemia cells against oxidative DNA damaging agents.

Kelley MR, Tritt R, Xu Y, New S, Freie B, Clapp DW, Deutsch WA. Kelley MR, et al. Among authors: xu y. Mutat Res. 2001 Mar 7;485(2):107-19. doi: 10.1016/s0921-8777(00)00067-7. Mutat Res. 2001. PMID: 11182542

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