Crain EJ - Search Results

1

Nonpeptide factor Xa inhibitors II. Antithrombotic evaluation in a rabbit model of electrically induced carotid artery thrombosis.

Wong PC, Crain EJ, Knabb RM, Meade RP, Quan ML, Watson CA, Wexler RR, Wright MR, Slee AM. Wong PC, et al. Among authors: crain ej. J Pharmacol Exp Ther. 2000 Oct;295(1):212-8. J Pharmacol Exp Ther. 2000. PMID: 10991981

2

Nonpeptide factor Xa inhibitors III: effects of DPC423, an orally-active pyrazole antithrombotic agent, on arterial thrombosis in rabbits.

Wong PC, Crain EJ, Watson CA, Zaspel AM, Wright MR, Lam PY, Pinto DJ, Wexler RR, Knabb RM. Wong PC, et al. Among authors: crain ej. J Pharmacol Exp Ther. 2002 Dec;303(3):993-1000. doi: 10.1124/jpet.102.040089. J Pharmacol Exp Ther. 2002. PMID: 12438519

3

Razaxaban, a direct factor Xa inhibitor, in combination with aspirin and/or clopidogrel improves low-dose antithrombotic activity without enhancing bleeding liability in rabbits.

Wong PC, Crain EJ, Watson CA, Wexler RR, Lam PY, Quan ML, Knabb RM. Wong PC, et al. Among authors: crain ej. J Thromb Thrombolysis. 2007 Aug;24(1):43-51. doi: 10.1007/s11239-007-0017-9. Epub 2007 Feb 24. J Thromb Thrombolysis. 2007. PMID: 17323133

4

In vitro, antithrombotic and bleeding time studies of BMS-654457, a small-molecule, reversible and direct inhibitor of factor XIa.

Wong PC, Quan ML, Watson CA, Crain EJ, Harpel MR, Rendina AR, Luettgen JM, Wexler RR, Schumacher WA, Seiffert DA. Wong PC, et al. Among authors: crain ej. J Thromb Thrombolysis. 2015 Nov;40(4):416-23. doi: 10.1007/s11239-015-1258-7. J Thromb Thrombolysis. 2015. PMID: 26249722

5

Antithrombotic actions of selective inhibitors of blood coagulation factor Xa in rat models of thrombosis.

Wong PC, Crain EJ Jr, Nguan O, Watson CA, Racanelli A. Wong PC, et al. Among authors: crain ej jr. Thromb Res. 1996 Jul 15;83(2):117-26. doi: 10.1016/0049-3848(96)00112-0. Thromb Res. 1996. PMID: 8837310

6

Nonpeptide factor Xa inhibitors: I. Studies with SF303 and SK549, a new class of potent antithrombotics.

Wong PC, Quan ML, Crain EJ, Watson CA, Wexler RR, Knabb RM. Wong PC, et al. Among authors: crain ej. J Pharmacol Exp Ther. 2000 Jan;292(1):351-7. J Pharmacol Exp Ther. 2000. PMID: 10604970

7

Apixaban, an oral, direct and highly selective factor Xa inhibitor: in vitro, antithrombotic and antihemostatic studies.

Wong PC, Crain EJ, Xin B, Wexler RR, Lam PY, Pinto DJ, Luettgen JM, Knabb RM. Wong PC, et al. Among authors: crain ej. J Thromb Haemost. 2008 May;6(5):820-9. doi: 10.1111/j.1538-7836.2008.02939.x. Epub 2008 Feb 25. J Thromb Haemost. 2008. PMID: 18315548 Free article.

8

Arterial antithrombotic and bleeding time effects of apixaban, a direct factor Xa inhibitor, in combination with antiplatelet therapy in rabbits.

Wong PC, Watson CA, Crain EJ. Wong PC, et al. Among authors: crain ej. J Thromb Haemost. 2008 Oct;6(10):1736-41. doi: 10.1111/j.1538-7836.2008.03092.x. Epub 2008 Jul 19. J Thromb Haemost. 2008. PMID: 18647224 Free article.

9

Favorable therapeutic index of the direct factor Xa inhibitors, apixaban and rivaroxaban, compared with the thrombin inhibitor dabigatran in rabbits.

Wong PC, Crain EJ, Watson CA, Xin B. Wong PC, et al. Among authors: crain ej. J Thromb Haemost. 2009 Aug;7(8):1313-20. doi: 10.1111/j.1538-7836.2009.03503.x. Epub 2009 Jun 3. J Thromb Haemost. 2009. PMID: 19500242 Free article.

10

Calibration and validation of the rabbit model of electrolytic-mediated arterial thrombosis against the standard-of-care anticoagulant apixaban.

Wong PC, Crain E. Wong PC, et al. Pharmacol Res Perspect. 2022 Jun;10(3):e00963. doi: 10.1002/prp2.963. Pharmacol Res Perspect. 2022. PMID: 35680619 Free PMC article.

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