Knabb RM - Search Results

1

Nonpeptide factor Xa inhibitors II. Antithrombotic evaluation in a rabbit model of electrically induced carotid artery thrombosis.

Wong PC, Crain EJ, Knabb RM, Meade RP, Quan ML, Watson CA, Wexler RR, Wright MR, Slee AM. Wong PC, et al. Among authors: knabb rm. J Pharmacol Exp Ther. 2000 Oct;295(1):212-8. J Pharmacol Exp Ther. 2000. PMID: 10991981

2

Nonpeptide factor Xa inhibitors: DPC423, a highly potent and orally bioavailable pyrazole antithrombotic agent.

Wong PC, Pinto DJ, Knabb RM. Wong PC, et al. Among authors: knabb rm. Cardiovasc Drug Rev. 2002 Summer;20(2):137-52. doi: 10.1111/j.1527-3466.2002.tb00188.x. Cardiovasc Drug Rev. 2002. PMID: 12177691 Review.

3

Nonpeptide factor Xa inhibitors III: effects of DPC423, an orally-active pyrazole antithrombotic agent, on arterial thrombosis in rabbits.

Wong PC, Crain EJ, Watson CA, Zaspel AM, Wright MR, Lam PY, Pinto DJ, Wexler RR, Knabb RM. Wong PC, et al. Among authors: knabb rm. J Pharmacol Exp Ther. 2002 Dec;303(3):993-1000. doi: 10.1124/jpet.102.040089. J Pharmacol Exp Ther. 2002. PMID: 12438519

4

Nonbenzamidine isoxazoline derivatives as factor Xa inhibitors.

Quan ML, Ellis CD, He MY, Liauw AY, Lam PY, Rossi KA, Knabb RM, Luettgen JM, Wright MR, Wong PC, Wexler RR. Quan ML, et al. Among authors: knabb rm. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1023-8. doi: 10.1016/s0960-894x(03)00080-5. Bioorg Med Chem Lett. 2003. PMID: 12643903

5

Razaxaban, a direct factor Xa inhibitor, in combination with aspirin and/or clopidogrel improves low-dose antithrombotic activity without enhancing bleeding liability in rabbits.

Wong PC, Crain EJ, Watson CA, Wexler RR, Lam PY, Quan ML, Knabb RM. Wong PC, et al. Among authors: knabb rm. J Thromb Thrombolysis. 2007 Aug;24(1):43-51. doi: 10.1007/s11239-007-0017-9. Epub 2007 Feb 24. J Thromb Thrombolysis. 2007. PMID: 17323133

6

Preparation of meta-amidino-N,N-disubstituted anilines as potent inhibitors of coagulation factor Xa.

Fevig JM, Cacciola J, Alexander RS, Knabb RM, Lam GN, Wong PC, Wexler RR. Fevig JM, et al. Among authors: knabb rm. Bioorg Med Chem Lett. 1998 Nov 17;8(22):3143-8. doi: 10.1016/s0960-894x(98)00574-5. Bioorg Med Chem Lett. 1998. PMID: 9873692

7

Preparation of pyrrolidine and isoxazolidine benzamidines as potent inhibitors of coagulation factor Xa.

Fevig JM, Buriak J Jr, Stouten PF, Knabb RM, Lam GN, Wong PC, Wexler RR. Fevig JM, et al. Among authors: knabb rm. Bioorg Med Chem Lett. 1999 Apr 19;9(8):1195-200. doi: 10.1016/s0960-894x(99)00164-x. Bioorg Med Chem Lett. 1999. PMID: 10328312

8

Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 1.

Quan ML, Liauw AY, Ellis CD, Pruitt JR, Carini DJ, Bostrom LL, Huang PP, Harrison K, Knabb RM, Thoolen MJ, Wong PC, Wexler RR. Quan ML, et al. Among authors: knabb rm. J Med Chem. 1999 Jul 29;42(15):2752-9. doi: 10.1021/jm980405i. J Med Chem. 1999. PMID: 10425086

9

Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 2.

Quan ML, Ellis CD, Liauw AY, Alexander RS, Knabb RM, Lam G, Wright MR, Wong PC, Wexler RR. Quan ML, et al. Among authors: knabb rm. J Med Chem. 1999 Jul 29;42(15):2760-73. doi: 10.1021/jm980406a. J Med Chem. 1999. PMID: 10425087

10

Nonpeptide factor Xa inhibitors: I. Studies with SF303 and SK549, a new class of potent antithrombotics.

Wong PC, Quan ML, Crain EJ, Watson CA, Wexler RR, Knabb RM. Wong PC, et al. Among authors: knabb rm. J Pharmacol Exp Ther. 2000 Jan;292(1):351-7. J Pharmacol Exp Ther. 2000. PMID: 10604970

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