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The GABA(B2) subunit is critical for the trafficking and function of native GABA(B) receptors.
Thuault SJ, Brown JT, Sheardown SA, Jourdain S, Fairfax B, Spencer JP, Restituito S, Nation JH, Topps S, Medhurst AD, Randall AD, Couve A, Moss SJ, Collingridge GL, Pangalos MN, Davies CH, Calver AR. Thuault SJ, et al. Among authors: calver ar. Biochem Pharmacol. 2004 Oct 15;68(8):1655-66. doi: 10.1016/j.bcp.2004.07.032. Biochem Pharmacol. 2004. PMID: 15451409
GABA(B2) is essential for g-protein coupling of the GABA(B) receptor heterodimer.
Robbins MJ, Calver AR, Filippov AK, Hirst WD, Russell RB, Wood MD, Nasir S, Couve A, Brown DA, Moss SJ, Pangalos MN. Robbins MJ, et al. Among authors: calver ar. J Neurosci. 2001 Oct 15;21(20):8043-52. doi: 10.1523/JNEUROSCI.21-20-08043.2001. J Neurosci. 2001. PMID: 11588177 Free PMC article.
Differences in the central nervous system distribution and pharmacology of the mouse 5-hydroxytryptamine-6 receptor compared with rat and human receptors investigated by radioligand binding, site-directed mutagenesis, and molecular modeling.
Hirst WD, Abrahamsen B, Blaney FE, Calver AR, Aloj L, Price GW, Medhurst AD. Hirst WD, et al. Among authors: calver ar. Mol Pharmacol. 2003 Dec;64(6):1295-308. doi: 10.1124/mol.64.6.1295. Mol Pharmacol. 2003. PMID: 14645659
38 results