Jacques SL - Search Results

1

Substrate-assisted catalysis of the PAR1 thrombin receptor. Enhancement of macromolecular association and cleavage.

Jacques SL, LeMasurier M, Sheridan PJ, Seeley SK, Kuliopulos A. Jacques SL, et al. J Biol Chem. 2000 Dec 29;275(52):40671-8. doi: 10.1074/jbc.M004544200. J Biol Chem. 2000. PMID: 11005807 Free article.

2

Protease-activated receptor-4 uses dual prolines and an anionic retention motif for thrombin recognition and cleavage.

Jacques SL, Kuliopulos A. Jacques SL, et al. Biochem J. 2003 Dec 15;376(Pt 3):733-40. doi: 10.1042/BJ20030954. Biochem J. 2003. PMID: 13678420 Free PMC article.

3

Structural basis for thrombin activation of a protease-activated receptor: inhibition of intramolecular liganding.

Seeley S, Covic L, Jacques SL, Sudmeier J, Baleja JD, Kuliopulos A. Seeley S, et al. Among authors: jacques sl. Chem Biol. 2003 Nov;10(11):1033-41. doi: 10.1016/j.chembiol.2003.10.014. Chem Biol. 2003. PMID: 14652070

4

PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells.

Boire A, Covic L, Agarwal A, Jacques S, Sherifi S, Kuliopulos A. Boire A, et al. Cell. 2005 Feb 11;120(3):303-13. doi: 10.1016/j.cell.2004.12.018. Cell. 2005. PMID: 15707890 Free article.

5

Blocking the protease-activated receptor 1-4 heterodimer in platelet-mediated thrombosis.

Leger AJ, Jacques SL, Badar J, Kaneider NC, Derian CK, Andrade-Gordon P, Covic L, Kuliopulos A. Leger AJ, et al. Among authors: jacques sl. Circulation. 2006 Mar 7;113(9):1244-54. doi: 10.1161/CIRCULATIONAHA.105.587758. Epub 2006 Feb 27. Circulation. 2006. PMID: 16505172

6

Pharmacology, biodistribution, and efficacy of GPCR-based pepducins in disease models.

Tressel SL, Koukos G, Tchernychev B, Jacques SL, Covic L, Kuliopulos A. Tressel SL, et al. Among authors: jacques sl. Methods Mol Biol. 2011;683:259-75. doi: 10.1007/978-1-60761-919-2_19. Methods Mol Biol. 2011. PMID: 21053136 Free PMC article. Review.

7

Pharmacodynamics and pharmacokinetics of the platelet GPIIb/IIIa inhibitor tirofiban in patients undergoing percutaneous coronary intervention: implications for adjustment of tirofiban and clopidogrel dosage.

Kimmelstiel C, Badar J, Covic L, Waxman S, Weintraub A, Jacques S, Kuliopulos A. Kimmelstiel C, et al. Thromb Res. 2005;116(1):55-66. doi: 10.1016/j.thromres.2004.11.011. Epub 2004 Dec 8. Thromb Res. 2005. PMID: 15850609 Clinical Trial.

8

Enzyme-assisted suicide: molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase.

Jacques SL, Mirza IA, Ejim L, Koteva K, Hughes DW, Green K, Kinach R, Honek JF, Lai HK, Berghuis AM, Wright GD. Jacques SL, et al. Chem Biol. 2003 Oct;10(10):989-95. doi: 10.1016/j.chembiol.2003.09.015. Chem Biol. 2003. PMID: 14583265

9

Crystallization and preliminary X-ray diffraction studies of homoserine dehydrogenase from Saccharomyces cerevisiae.

DeLaBarre B, Jacques SL, Pratt CE, Ruth DA, Wright GD, Berghuis AM. DeLaBarre B, et al. Among authors: jacques sl. Acta Crystallogr D Biol Crystallogr. 1998 May 1;54(Pt 3):413-5. doi: 10.1107/s0907444997011967. Acta Crystallogr D Biol Crystallogr. 1998. PMID: 9761913

10

Characterization of yeast homoserine dehydrogenase, an antifungal target: the invariant histidine 309 is important for enzyme integrity.

Jacques SL, Nieman C, Bareich D, Broadhead G, Kinach R, Honek JF, Wright GD. Jacques SL, et al. Biochim Biophys Acta. 2001 Jan 12;1544(1-2):28-41. doi: 10.1016/s0167-4838(00)00203-x. Biochim Biophys Acta. 2001. PMID: 11341914

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