Spong S - Search Results

1

Parenteral administration of an activating monoclonal antibody to the alpha1beta1 integrin in dogs.

Bank I, Hardan I, Lokshin E, Nas D, Miron S, Ohad D, Spong S, Garrod DR. Bank I, et al. Among authors: spong s. Immunobiology. 2000 Sep;202(3):239-53. doi: 10.1016/s0171-2985(00)80031-5. Immunobiology. 2000. PMID: 11045660

2

The integrin alphavbeta6 is critical for keratinocyte migration on both its known ligand, fibronectin, and on vitronectin.

Huang X, Wu J, Spong S, Sheppard D. Huang X, et al. Among authors: spong s. J Cell Sci. 1998 Aug;111 ( Pt 15):2189-95. doi: 10.1242/jcs.111.15.2189. J Cell Sci. 1998. PMID: 9664040

3

Targeting connective tissue growth factor (CTGF) in acute lymphoblastic leukemia preclinical models: anti-CTGF monoclonal antibody attenuates leukemia growth.

Lu H, Kojima K, Battula VL, Korchin B, Shi Y, Chen Y, Spong S, Thomas DA, Kantarjian H, Lock RB, Andreeff M, Konopleva M. Lu H, et al. Among authors: spong s. Ann Hematol. 2014 Mar;93(3):485-492. doi: 10.1007/s00277-013-1939-2. Epub 2013 Oct 24. Ann Hematol. 2014. PMID: 24154679 Free PMC article.

4

Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis.

Dornhöfer N, Spong S, Bennewith K, Salim A, Klaus S, Kambham N, Wong C, Kaper F, Sutphin P, Nacamuli R, Höckel M, Le Q, Longaker M, Yang G, Koong A, Giaccia A. Dornhöfer N, et al. Among authors: spong s. Cancer Res. 2006 Jun 1;66(11):5816-27. doi: 10.1158/0008-5472.CAN-06-0081. Cancer Res. 2006. PMID: 16740721

5

CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer.

Neesse A, Frese KK, Bapiro TE, Nakagawa T, Sternlicht MD, Seeley TW, Pilarsky C, Jodrell DI, Spong SM, Tuveson DA. Neesse A, et al. Among authors: spong sm. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12325-30. doi: 10.1073/pnas.1300415110. Epub 2013 Jul 8. Proc Natl Acad Sci U S A. 2013. PMID: 23836645 Free PMC article.

6

Expression of connective tissue growth factor in pancreatic cancer cell lines.

Kwon S, Munroe X, Crawley SC, Lee HY, Spong S, Bradham D, Gum JR Jr, Sleisenger MH, Kim YS. Kwon S, et al. Among authors: spong s. Int J Oncol. 2007 Oct;31(4):693-703. Int J Oncol. 2007. PMID: 17786299

7

Connective tissue growth factor-specific antibody attenuates tumor growth, metastasis, and angiogenesis in an orthotopic mouse model of pancreatic cancer.

Aikawa T, Gunn J, Spong SM, Klaus SJ, Korc M. Aikawa T, et al. Among authors: spong sm. Mol Cancer Ther. 2006 May;5(5):1108-16. doi: 10.1158/1535-7163.MCT-05-0516. Mol Cancer Ther. 2006. PMID: 16731742

8

CTGF is a therapeutic target for metastatic melanoma.

Finger EC, Cheng CF, Williams TR, Rankin EB, Bedogni B, Tachiki L, Spong S, Giaccia AJ, Powell MB. Finger EC, et al. Among authors: spong s. Oncogene. 2014 Feb 27;33(9):1093-100. doi: 10.1038/onc.2013.47. Epub 2013 Feb 25. Oncogene. 2014. PMID: 23435419 Free PMC article.

9

Connective tissue growth factor as a novel therapeutic target in high grade serous ovarian cancer.

Moran-Jones K, Gloss BS, Murali R, Chang DK, Colvin EK, Jones MD, Yuen S, Howell VM, Brown LM, Wong CW, Spong SM, Scarlett CJ, Hacker NF, Ghosh S, Mok SC, Birrer MJ, Samimi G. Moran-Jones K, et al. Among authors: spong sm. Oncotarget. 2015 Dec 29;6(42):44551-62. doi: 10.18632/oncotarget.6082. Oncotarget. 2015. PMID: 26575166 Free PMC article.

10

CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis.

Lipson KE, Wong C, Teng Y, Spong S. Lipson KE, et al. Among authors: spong s. Fibrogenesis Tissue Repair. 2012 Jun 6;5(Suppl 1):S24. doi: 10.1186/1755-1536-5-S1-S24. eCollection 2012. Fibrogenesis Tissue Repair. 2012. PMID: 23259531 Free PMC article.

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