Hawes BE - Search Results

1

The melanin-concentrating hormone receptor couples to multiple G proteins to activate diverse intracellular signaling pathways.

Hawes BE, Kil E, Green B, O'Neill K, Fried S, Graziano MP. Hawes BE, et al. Endocrinology. 2000 Dec;141(12):4524-32. doi: 10.1210/endo.141.12.7833. Endocrinology. 2000. PMID: 11108264

2

Cloning and characterization of rhesus monkey MCH-R1 and MCH-R2.

Fried S, O'Neill K, Hawes BE. Fried S, et al. Among authors: hawes be. Peptides. 2002 Aug;23(8):1401-8. doi: 10.1016/s0196-9781(02)00077-3. Peptides. 2002. PMID: 12182940

3

Identification and pharmacological characterization of a novel human melanin-concentrating hormone receptor, mch-r2.

Wang S, Behan J, O'Neill K, Weig B, Fried S, Laz T, Bayne M, Gustafson E, Hawes BE. Wang S, et al. Among authors: hawes be. J Biol Chem. 2001 Sep 14;276(37):34664-70. doi: 10.1074/jbc.M102601200. Epub 2001 Jul 17. J Biol Chem. 2001. PMID: 11459838 Free article.

4

Differential intracellular signaling of the GalR1 and GalR2 galanin receptor subtypes.

Wang S, Hashemi T, Fried S, Clemmons AL, Hawes BE. Wang S, et al. Among authors: hawes be. Biochemistry. 1998 May 12;37(19):6711-7. doi: 10.1021/bi9728405. Biochemistry. 1998. PMID: 9578554

5

Nociceptin (ORL-1) and mu-opioid receptors mediate mitogen-activated protein kinase activation in CHO cells through a Gi-coupled signaling pathway: evidence for distinct mechanisms of agonist-mediated desensitization.

Hawes BE, Fried S, Yao X, Weig B, Graziano MP. Hawes BE, et al. J Neurochem. 1998 Sep;71(3):1024-33. doi: 10.1046/j.1471-4159.1998.71031024.x. J Neurochem. 1998. PMID: 9721727 Free article.

6

Cellular actions of nociceptin: transduction mechanisms.

Hawes BE, Graziano MP, Lambert DG. Hawes BE, et al. Peptides. 2000 Jul;21(7):961-7. doi: 10.1016/s0196-9781(00)00232-1. Peptides. 2000. PMID: 10998529 Review.

7

Identification and characterization of single-nucleotide polymorphisms in MCH-R1 and MCH-R2.

Hawes BE, Green B, O'Neill K, Fried S, Arreaza MG, Qiu P, Simon JS. Hawes BE, et al. Obes Res. 2004 Aug;12(8):1327-34. doi: 10.1038/oby.2004.167. Obes Res. 2004. PMID: 15340116 Free article.

8

Discovery of melanin-concentrating hormone receptor R1 antagonists using high-throughput synthesis.

Su J, McKittrick BA, Tang H, Czarniecki M, Greenlee WJ, Hawes BE, O'Neill K. Su J, et al. Among authors: hawes be. Bioorg Med Chem. 2005 Mar 1;13(5):1829-36. doi: 10.1016/j.bmc.2004.11.046. Bioorg Med Chem. 2005. PMID: 15698800

9

Effects of a selective melanin-concentrating hormone 1 receptor antagonist on food intake and energy homeostasis in diet-induced obese mice.

Kowalski TJ, Spar BD, Weig B, Farley C, Cook J, Ghibaudi L, Fried S, O'Neill K, Del Vecchio RA, McBriar M, Guzik H, Clader J, Hawes BE, Hwa J. Kowalski TJ, et al. Among authors: hawes be. Eur J Pharmacol. 2006 Mar 27;535(1-3):182-91. doi: 10.1016/j.ejphar.2006.01.062. Epub 2006 Mar 13. Eur J Pharmacol. 2006. PMID: 16540104

10

Synthesis and structure-activity relationships of piperidine-based melanin-concentrating hormone receptor 1 antagonists.

Wu WL, Burnett DA, Spring R, Qiang L, Sasikumar TK, Domalski MS, Greenlee WJ, O'Neill K, Hawes BE. Wu WL, et al. Among authors: hawes be. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3668-73. doi: 10.1016/j.bmcl.2006.04.061. Epub 2006 May 11. Bioorg Med Chem Lett. 2006. PMID: 16690312

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