Lu D - Search Results

1

Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells.

Mulder H, Lu D, Finley J 4th, An J, Cohen J, Antinozzi PA, McGarry JD, Newgard CB. Mulder H, et al. Among authors: lu d. J Biol Chem. 2001 Mar 2;276(9):6479-84. doi: 10.1074/jbc.M010364200. Epub 2000 Dec 11. J Biol Chem. 2001. PMID: 11113153 Free article.

2

Biochemical mechanism of lipid-induced impairment of glucose-stimulated insulin secretion and reversal with a malate analogue.

Boucher A, Lu D, Burgess SC, Telemaque-Potts S, Jensen MV, Mulder H, Wang MY, Unger RH, Sherry AD, Newgard CB. Boucher A, et al. Among authors: lu d. J Biol Chem. 2004 Jun 25;279(26):27263-71. doi: 10.1074/jbc.M401167200. Epub 2004 Apr 7. J Biol Chem. 2004. PMID: 15073188 Free article.

3

Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion.

Jensen MV, Joseph JW, Ilkayeva O, Burgess S, Lu D, Ronnebaum SM, Odegaard M, Becker TC, Sherry AD, Newgard CB. Jensen MV, et al. Among authors: lu d. J Biol Chem. 2006 Aug 4;281(31):22342-22351. doi: 10.1074/jbc.M604350200. Epub 2006 Jun 1. J Biol Chem. 2006. PMID: 16740637 Free article.

4

13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS).

Lu D, Mulder H, Zhao P, Burgess SC, Jensen MV, Kamzolova S, Newgard CB, Sherry AD. Lu D, et al. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2708-13. doi: 10.1073/pnas.052005699. Proc Natl Acad Sci U S A. 2002. PMID: 11880625 Free PMC article.

5

A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion.

Ronnebaum SM, Ilkayeva O, Burgess SC, Joseph JW, Lu D, Stevens RD, Becker TC, Sherry AD, Newgard CB, Jensen MV. Ronnebaum SM, et al. Among authors: lu d. J Biol Chem. 2006 Oct 13;281(41):30593-602. doi: 10.1074/jbc.M511908200. Epub 2006 Aug 15. J Biol Chem. 2006. PMID: 16912049 Free article.

6

The role of AMPK and mTOR in nutrient sensing in pancreatic beta-cells.

Gleason CE, Lu D, Witters LA, Newgard CB, Birnbaum MJ. Gleason CE, et al. Among authors: lu d. J Biol Chem. 2007 Apr 6;282(14):10341-51. doi: 10.1074/jbc.M610631200. Epub 2007 Feb 7. J Biol Chem. 2007. PMID: 17287212 Free article.

7

Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism.

Ronnebaum SM, Joseph JW, Ilkayeva O, Burgess SC, Lu D, Becker TC, Sherry AD, Newgard CB. Ronnebaum SM, et al. Among authors: lu d. J Biol Chem. 2008 May 23;283(21):14248-56. doi: 10.1074/jbc.M800119200. Epub 2008 Apr 1. J Biol Chem. 2008. PMID: 18381287 Free PMC article.

8

Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets.

Ronnebaum SM, Jensen MV, Hohmeier HE, Burgess SC, Zhou YP, Qian S, MacNeil D, Howard A, Thornberry N, Ilkayeva O, Lu D, Sherry AD, Newgard CB. Ronnebaum SM, et al. Among authors: lu d. J Biol Chem. 2008 Oct 24;283(43):28909-17. doi: 10.1074/jbc.M804665200. Epub 2008 Aug 28. J Biol Chem. 2008. PMID: 18755687 Free PMC article.

9

The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion.

Odegaard ML, Joseph JW, Jensen MV, Lu D, Ilkayeva O, Ronnebaum SM, Becker TC, Newgard CB. Odegaard ML, et al. Among authors: lu d. J Biol Chem. 2010 May 28;285(22):16530-7. doi: 10.1074/jbc.M109.092593. Epub 2010 Mar 31. J Biol Chem. 2010. PMID: 20356834 Free PMC article.

10

Control of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion.

Jensen MV, Haldeman JM, Zhang H, Lu D, Huising MO, Vale WW, Hohmeier HE, Rosenberg P, Newgard CB. Jensen MV, et al. Among authors: lu d. J Biol Chem. 2013 Aug 9;288(32):23128-40. doi: 10.1074/jbc.M113.491654. Epub 2013 Jun 20. J Biol Chem. 2013. PMID: 23788641 Free PMC article.

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