Bowtell D - Search Results

1

Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility.

Sanjay A, Houghton A, Neff L, DiDomenico E, Bardelay C, Antoine E, Levy J, Gailit J, Bowtell D, Horne WC, Baron R. Sanjay A, et al. Among authors: bowtell d. J Cell Biol. 2001 Jan 8;152(1):181-95. doi: 10.1083/jcb.152.1.181. J Cell Biol. 2001. PMID: 11149930 Free PMC article.

2

The Cbl proto-oncogene product negatively regulates the Src-family tyrosine kinase Fyn by enhancing its degradation.

Andoniou CE, Lill NL, Thien CB, Lupher ML Jr, Ota S, Bowtell DD, Scaife RM, Langdon WY, Band H. Andoniou CE, et al. Among authors: bowtell dd. Mol Cell Biol. 2000 Feb;20(3):851-67. doi: 10.1128/MCB.20.3.851-867.2000. Mol Cell Biol. 2000. PMID: 10629042 Free PMC article.

3

TGF-beta, c-Cbl, and PDGFR-alpha the in mammary stroma.

Crowley MR, Bowtell D, Serra R. Crowley MR, et al. Among authors: bowtell d. Dev Biol. 2005 Mar 1;279(1):58-72. doi: 10.1016/j.ydbio.2004.11.034. Dev Biol. 2005. PMID: 15708558 Free article.

4

Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice.

Murphy MA, Schnall RG, Venter DJ, Barnett L, Bertoncello I, Thien CB, Langdon WY, Bowtell DD. Murphy MA, et al. Among authors: bowtell dd. Mol Cell Biol. 1998 Aug;18(8):4872-82. doi: 10.1128/MCB.18.8.4872. Mol Cell Biol. 1998. PMID: 9671496 Free PMC article.

5

Regulation of STAT protein synthesis by c-Cbl.

Blesofsky WA, Mowen K, Arduini RM, Baker DP, Murphy MA, Bowtell DD, David M. Blesofsky WA, et al. Among authors: bowtell dd. Oncogene. 2001 Nov 1;20(50):7326-33. doi: 10.1038/sj.onc.1204919. Oncogene. 2001. PMID: 11704862

6

An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response.

Calzado MA, de la Vega L, Möller A, Bowtell DD, Schmitz ML. Calzado MA, et al. Among authors: bowtell dd. Nat Cell Biol. 2009 Jan;11(1):85-91. doi: 10.1038/ncb1816. Epub 2008 Nov 30. Nat Cell Biol. 2009. PMID: 19043406

7

Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.

Simon MA, Bowtell DD, Dodson GS, Laverty TR, Rubin GM. Simon MA, et al. Among authors: bowtell dd. Cell. 1991 Nov 15;67(4):701-16. doi: 10.1016/0092-8674(91)90065-7. Cell. 1991. PMID: 1934068

8

A mouse with a loss-of-function mutation in the c-Cbl TKB domain shows perturbed thymocyte signaling without enhancing the activity of the ZAP-70 tyrosine kinase.

Thien CB, Scaife RM, Papadimitriou JM, Murphy MA, Bowtell DD, Langdon WY. Thien CB, et al. Among authors: bowtell dd. J Exp Med. 2003 Feb 17;197(4):503-13. doi: 10.1084/jem.20021498. J Exp Med. 2003. PMID: 12591907 Free PMC article.

9

Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma.

Thomas DM, Johnson SA, Sims NA, Trivett MK, Slavin JL, Rubin BP, Waring P, McArthur GA, Walkley CR, Holloway AJ, Diyagama D, Grim JE, Clurman BE, Bowtell DD, Lee JS, Gutierrez GM, Piscopo DM, Carty SA, Hinds PW. Thomas DM, et al. Among authors: bowtell dd. J Cell Biol. 2004 Dec 6;167(5):925-34. doi: 10.1083/jcb.200409187. J Cell Biol. 2004. PMID: 15583032 Free PMC article.

10

The protein product of the c-cbl oncogene rapidly complexes with the EGF receptor and is tyrosine phosphorylated following EGF stimulation.

Bowtell DD, Langdon WY. Bowtell DD, et al. Oncogene. 1995 Oct 19;11(8):1561-7. Oncogene. 1995. PMID: 7478580

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