Houghton A - Search Results

1

Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility.

Sanjay A, Houghton A, Neff L, DiDomenico E, Bardelay C, Antoine E, Levy J, Gailit J, Bowtell D, Horne WC, Baron R. Sanjay A, et al. Among authors: houghton a. J Cell Biol. 2001 Jan 8;152(1):181-95. doi: 10.1083/jcb.152.1.181. J Cell Biol. 2001. PMID: 11149930 Free PMC article.

2

Leucine zipper-mediated homodimerization of the adaptor protein c-Cbl. A role in c-Cbl's tyrosine phosphorylation and its association with epidermal growth factor receptor.

Bartkiewicz M, Houghton A, Baron R. Bartkiewicz M, et al. Among authors: houghton a. J Biol Chem. 1999 Oct 22;274(43):30887-95. doi: 10.1074/jbc.274.43.30887. J Biol Chem. 1999. PMID: 10521482 Free article.

3

Src-catalyzed phosphorylation of c-Cbl leads to the interdependent ubiquitination of both proteins.

Yokouchi M, Kondo T, Sanjay A, Houghton A, Yoshimura A, Komiya S, Zhang H, Baron R. Yokouchi M, et al. Among authors: houghton a. J Biol Chem. 2001 Sep 14;276(37):35185-93. doi: 10.1074/jbc.M102219200. Epub 2001 Jul 11. J Biol Chem. 2001. PMID: 11448952 Free article.

4

The tyrosine phosphatase SHP-1 is a negative regulator of osteoclastogenesis and osteoclast resorbing activity: increased resorption and osteopenia in me(v)/me(v) mutant mice.

Aoki K, Didomenico E, Sims NA, Mukhopadhyay K, Neff L, Houghton A, Amling M, Levy JB, Horne WC, Baron R. Aoki K, et al. Among authors: houghton a. Bone. 1999 Sep;25(3):261-7. doi: 10.1016/s8756-3282(99)00174-x. Bone. 1999. PMID: 10495129 Free article.

5

Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7.

Yokouchi M, Kondo T, Houghton A, Bartkiewicz M, Horne WC, Zhang H, Yoshimura A, Baron R. Yokouchi M, et al. Among authors: houghton a. J Biol Chem. 1999 Oct 29;274(44):31707-12. doi: 10.1074/jbc.274.44.31707. J Biol Chem. 1999. PMID: 10531381 Free article.

6

Good cops turn bad: The contribution of neutrophils to immune-checkpoint inhibitor treatment failures in cancer.

Zhang H, Houghton AM. Zhang H, et al. Among authors: houghton am. Pharmacol Ther. 2021 Jan;217:107662. doi: 10.1016/j.pharmthera.2020.107662. Epub 2020 Aug 15. Pharmacol Ther. 2021. PMID: 32805297 Review.

7

Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy.

Hidvegi T, Stolz DB, Alcorn JF, Yousem SA, Wang J, Leme AS, Houghton AM, Hale P, Ewing M, Cai H, Garchar EA, Pastore N, Annunziata P, Kaminski N, Pilewski J, Shapiro SD, Pak SC, Silverman GA, Brunetti-Pierri N, Perlmutter DH. Hidvegi T, et al. Among authors: houghton am. J Biol Chem. 2015 Dec 11;290(50):29742-57. doi: 10.1074/jbc.M115.691253. Epub 2015 Oct 22. J Biol Chem. 2015. PMID: 26494620 Free PMC article.

8

Immortalization of human marrow stromal cells by retroviral transduction with a temperature sensitive oncogene: identification of bipotential precursor cells capable of directed differentiation to either an osteoblast or adipocyte phenotype.

Houghton A, Oyajobi BO, Foster GA, Russell RG, Stringer BM. Houghton A, et al. Bone. 1998 Jan;22(1):7-16. doi: 10.1016/s8756-3282(97)00229-9. Bone. 1998. PMID: 9437508

9

Macrophage-Dependent Cytoplasmic Transfer during Melanoma Invasion In Vivo.

Roh-Johnson M, Shah AN, Stonick JA, Poudel KR, Kargl J, Yang GH, di Martino J, Hernandez RE, Gast CE, Zarour LR, Antoku S, Houghton AM, Bravo-Cordero JJ, Wong MH, Condeelis J, Moens CB. Roh-Johnson M, et al. Among authors: houghton am. Dev Cell. 2017 Dec 4;43(5):549-562.e6. doi: 10.1016/j.devcel.2017.11.003. Dev Cell. 2017. PMID: 29207258 Free PMC article.

10

MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity.

Grunblatt E, Wu N, Zhang H, Liu X, Norton JP, Ohol Y, Leger P, Hiatt JB, Eastwood EC, Thomas R, Ibrahim AH, Jia D, Basom R, Eaton KD, Martins R, Houghton AM, MacPherson D. Grunblatt E, et al. Among authors: houghton am. Genes Dev. 2020 Sep 1;34(17-18):1210-1226. doi: 10.1101/gad.340133.120. Epub 2020 Aug 20. Genes Dev. 2020. PMID: 32820040 Free PMC article.

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