Bookser BC - Search Results

1

AMP deaminase inhibitors. 5. Design, synthesis, and SAR of a highly potent inhibitor series.

Kasibhatla SR, Bookser BC, Xiao W, Erion MD. Kasibhatla SR, et al. Among authors: bookser bc. J Med Chem. 2001 Feb 15;44(4):613-8. doi: 10.1021/jm000355t. J Med Chem. 2001. PMID: 11170651

2

Adenosine kinase inhibitors. 6. Synthesis, water solubility, and antinociceptive activity of 5-phenyl-7-(5-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidines substituted at C4 with glycinamides and related compounds.

Bookser BC, Ugarkar BG, Matelich MC, Lemus RH, Allan M, Tsuchiya M, Nakane M, Nagahisa A, Wiesner JB, Erion MD. Bookser BC, et al. J Med Chem. 2005 Dec 1;48(24):7808-20. doi: 10.1021/jm050394a. J Med Chem. 2005. PMID: 16302820

3

Design, synthesis, and structure-activity relationships of the first highly potent, selective, and bioavailable adenosine 5'-monophosphate deaminase inhibitors.

Kasibhatla SR, Bookser BC, Appleman JR, Probst G, Xiao W, Fujitaki JM, Erion MD. Kasibhatla SR, et al. Among authors: bookser bc. Adv Exp Med Biol. 1998;431:849-52. doi: 10.1007/978-1-4615-5381-6_163. Adv Exp Med Biol. 1998. PMID: 9598183

4

Design and synthesis of the first potent, selective, and cell penetrating adenosine 5'-monophosphate deaminase inhibitors.

Bookser BC, Kasibhatla SR, Appleman JR, Erion MD. Bookser BC, et al. Adv Exp Med Biol. 1998;431:853-7. doi: 10.1007/978-1-4615-5381-6_164. Adv Exp Med Biol. 1998. PMID: 9598184

5

AMP deaminase inhibitors. 2. Initial discovery of a non-nucleotide transition-state inhibitor series.

Bookser BC, Kasibhatla SR, Appleman JR, Erion MD. Bookser BC, et al. J Med Chem. 2000 Apr 20;43(8):1495-507. doi: 10.1021/jm990447m. J Med Chem. 2000. PMID: 10780906

6

AMP deaminase inhibitors. 3. SAR of 3-(carboxyarylalkyl)coformycin aglycon analogues.

Kasibhatla SR, Bookser BC, Probst G, Appleman JR, Erion MD. Kasibhatla SR, et al. Among authors: bookser bc. J Med Chem. 2000 Apr 20;43(8):1508-18. doi: 10.1021/jm990448e. J Med Chem. 2000. PMID: 10780907

7

AMP deaminase inhibitors. 4. Further N3-substituted coformycin aglycon analogues: N3-alkylmalonates as ribose 5'-monophosphate mimetics.

Bookser BC, Kasibhatla SR, Erion MD. Bookser BC, et al. J Med Chem. 2000 Apr 20;43(8):1519-24. doi: 10.1021/jm9905413. J Med Chem. 2000. PMID: 10780908

8

Synthesis of 3'-amino-3'-deoxyguanosine and 3'-amino-3'-deoxyxyloguanosine monophosphate HepDirect prodrugs from guanosine.

Bookser BC, Raffaele NB, Reddy KR, Fan K, Huang W, Erion MD. Bookser BC, et al. Nucleosides Nucleotides Nucleic Acids. 2009 Oct;28(10):969-86. doi: 10.1080/15257770903307151. Nucleosides Nucleotides Nucleic Acids. 2009. PMID: 20183565

9

Adenosine kinase inhibitors. 4. 6,8-Disubstituted purine nucleoside derivatives. Synthesis, conformation, and enzyme inhibition.

Bookser BC, Matelich MC, Ollis K, Ugarkar BG. Bookser BC, et al. J Med Chem. 2005 May 5;48(9):3389-99. doi: 10.1021/jm048968j. J Med Chem. 2005. PMID: 15857145

10

Design and Synthesis of Novel and Selective Glycine Transporter-1 (GlyT1) Inhibitors with Memory Enhancing Properties.

Santora VJ, Almos TA, Barido R, Basinger J, Bellows CL, Bookser BC, Breitenbucher JG, Broadbent NJ, Cabebe C, Chai CK, Chen M, Chow S, Chung M, Crickard L, Danks AM, Freestone GC, Gitnick D, Gupta V, Hoffmaster C, Hudson AR, Kaplan AP, Kennedy MR, Lee D, Limberis J, Ly K, Mak CC, Masatsugu B, Morse AC, Na J, Neul D, Nikpur J, Peters M, Petroski RE, Renick J, Sebring K, Sevidal S, Tabatabaei A, Wen J, Yan Y, Yoder ZW, Zook D. Santora VJ, et al. Among authors: bookser bc. J Med Chem. 2018 Jul 26;61(14):6018-6033. doi: 10.1021/acs.jmedchem.8b00372. Epub 2018 Jul 11. J Med Chem. 2018. PMID: 29886732

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