Santarelli L - Search Results

1

Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function.

Santarelli L, Gobbi G, Debs PC, Sibille ET, Blier P, Hen R, Heath MJ. Santarelli L, et al. Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1912-7. doi: 10.1073/pnas.98.4.1912. Epub 2001 Jan 30. Proc Natl Acad Sci U S A. 2001. PMID: 11172050 Free PMC article.

2

Behavioral and physiologic effects of genetic or pharmacologic inactivation of the substance P receptor (NK1).

Santarelli L, Gobbi G, Blier P, Hen R. Santarelli L, et al. J Clin Psychiatry. 2002;63 Suppl 11:11-7. J Clin Psychiatry. 2002. PMID: 12562138 Review.

3

Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult.

Gross C, Zhuang X, Stark K, Ramboz S, Oosting R, Kirby L, Santarelli L, Beck S, Hen R. Gross C, et al. Among authors: santarelli l. Nature. 2002 Mar 28;416(6879):396-400. doi: 10.1038/416396a. Nature. 2002. PMID: 11919622

4

Neurokinin 1 receptor antagonism requires norepinephrine to increase serotonin function.

Gobbi G, Cassano T, Radja F, Morgese MG, Cuomo V, Santarelli L, Hen R, Blier P. Gobbi G, et al. Among authors: santarelli l. Eur Neuropsychopharmacol. 2007 Apr;17(5):328-38. doi: 10.1016/j.euroneuro.2006.07.004. Epub 2006 Sep 6. Eur Neuropsychopharmacol. 2007. PMID: 16950604

5

Altered emotional states in knockout mice lacking 5-HT1A or 5-HT1B receptors.

Zhuang X, Gross C, Santarelli L, Compan V, Trillat AC, Hen R. Zhuang X, et al. Among authors: santarelli l. Neuropsychopharmacology. 1999 Aug;21(2 Suppl):52S-60S. doi: 10.1016/S0893-133X(99)00047-0. Neuropsychopharmacology. 1999. PMID: 10432489 Review.

6

Altered fear circuits in 5-HT(1A) receptor KO mice.

Gross C, Santarelli L, Brunner D, Zhuang X, Hen R. Gross C, et al. Among authors: santarelli l. Biol Psychiatry. 2000 Dec 15;48(12):1157-63. doi: 10.1016/s0006-3223(00)01041-6. Biol Psychiatry. 2000. PMID: 11137057 Free article. Review.

7

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants.

Santarelli L, Saxe M, Gross C, Surget A, Battaglia F, Dulawa S, Weisstaub N, Lee J, Duman R, Arancio O, Belzung C, Hen R. Santarelli L, et al. Science. 2003 Aug 8;301(5634):805-9. doi: 10.1126/science.1083328. Science. 2003. PMID: 12907793

8

Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus.

Saxe MD, Battaglia F, Wang JW, Malleret G, David DJ, Monckton JE, Garcia AD, Sofroniew MV, Kandel ER, Santarelli L, Hen R, Drew MR. Saxe MD, et al. Among authors: santarelli l. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17501-6. doi: 10.1073/pnas.0607207103. Epub 2006 Nov 6. Proc Natl Acad Sci U S A. 2006. PMID: 17088541 Free PMC article.

9

Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: relevance to the antidepressant/anxiolytic response.

Blier P, Gobbi G, Haddjeri N, Santarelli L, Mathew G, Hen R. Blier P, et al. Among authors: santarelli l. J Psychiatry Neurosci. 2004 May;29(3):208-18. J Psychiatry Neurosci. 2004. PMID: 15173897 Free PMC article.

10

Efficacy of the MCHR1 antagonist N-[3-(1-{[4-(3,4-difluorophenoxy)phenyl]methyl}(4-piperidyl))-4-methylphenyl]-2-methylpropanamide (SNAP 94847) in mouse models of anxiety and depression following acute and chronic administration is independent of hippocampal neurogenesis.

David DJ, Klemenhagen KC, Holick KA, Saxe MD, Mendez I, Santarelli L, Craig DA, Zhong H, Swanson CJ, Hegde LG, Ping XI, Dong D, Marzabadi MR, Gerald CP, Hen R. David DJ, et al. Among authors: santarelli l. J Pharmacol Exp Ther. 2007 Apr;321(1):237-48. doi: 10.1124/jpet.106.109678. Epub 2007 Jan 19. J Pharmacol Exp Ther. 2007. PMID: 17237257

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