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Intron variants of the p53 gene are associated with increased risk for ovarian cancer but not in carriers of BRCA1 or BRCA2 germline mutations.
Wang-Gohrke S, Weikel W, Risch H, Vesprini D, Abrahamson J, Lerman C, Godwin A, Moslehi R, Olipade O, Brunet JS, Stickeler E, Kieback DG, Kreienberg R, Weber B, Narod SA, Runnebaum IB. Wang-Gohrke S, et al. Br J Cancer. 1999 Sep;81(1):179-83. doi: 10.1038/sj.bjc.6690669. Br J Cancer. 1999. PMID: 10487631 Free PMC article.
HPC2 variants and screen-detected prostate cancer.
Vesprini D, Nam RK, Trachtenberg J, Jewett MA, Tavtigian SV, Emami M, Ho M, Toi A, Narod SA. Vesprini D, et al. Am J Hum Genet. 2001 Apr;68(4):912-7. doi: 10.1086/319502. Epub 2001 Mar 14. Am J Hum Genet. 2001. PMID: 11254449 Free PMC article.
Progesterone receptor variant increases ovarian cancer risk in BRCA1 and BRCA2 mutation carriers who were never exposed to oral contraceptives.
Runnebaum IB, Wang-Gohrke S, Vesprini D, Kreienberg R, Lynch H, Moslehi R, Ghadirian P, Weber B, Godwin AK, Risch H, Garber J, Lerman C, Olopade OI, Foulkes WD, Karlan B, Warner E, Rosen B, Rebbeck T, Tonin P, Dubé MP, Kieback DG, Narod SA. Runnebaum IB, et al. Pharmacogenetics. 2001 Oct;11(7):635-8. doi: 10.1097/00008571-200110000-00010. Pharmacogenetics. 2001. PMID: 11668223
Risk of ipsilateral breast cancer in BRCA1 and BRCA2 mutation carriers.
Metcalfe K, Lynch HT, Ghadirian P, Tung N, Kim-Sing C, Olopade OI, Domchek S, Eisen A, Foulkes WD, Rosen B, Vesprini D, Sun P, Narod SA. Metcalfe K, et al. Breast Cancer Res Treat. 2011 May;127(1):287-96. doi: 10.1007/s10549-010-1336-7. Epub 2011 Jan 9. Breast Cancer Res Treat. 2011. PMID: 21221768
139 results