Yoshino T - Search Results

1

Orally active docetaxel analogue: synthesis of 10-deoxy-10-C-morpholinoethyl docetaxel analogues.

Iimura S, Uoto K, Ohsuki S, Chiba J, Yoshino T, Iwahana M, Jimbo T, Terasawa H, Soga T. Iimura S, et al. Among authors: yoshino t. Bioorg Med Chem Lett. 2001 Feb 12;11(3):407-10. doi: 10.1016/s0960-894x(00)00682-x. Bioorg Med Chem Lett. 2001. PMID: 11212122

2

New highly active taxoids from 9beta-dihydrobaccatin-9,10-acetals. Part 2.

Ishiyama T, Iimura S, Yoshino T, Chiba J, Uoto K, Terasawa H, Soga T. Ishiyama T, et al. Among authors: yoshino t. Bioorg Med Chem Lett. 2002 Oct 21;12(20):2815-9. doi: 10.1016/s0960-894x(02)00628-5. Bioorg Med Chem Lett. 2002. PMID: 12270153

3

New highly active taxoids from 9beta-dihydrobaccatin-9,10-acetals. Part 3.

Takeda Y, Yoshino T, Uoto K, Chiba J, Ishiyama T, Iwahana M, Jimbo T, Tanaka N, Terasawa H, Soga T. Takeda Y, et al. Among authors: yoshino t. Bioorg Med Chem Lett. 2003 Jan 20;13(2):185-90. doi: 10.1016/s0960-894x(02)00891-0. Bioorg Med Chem Lett. 2003. PMID: 12482420

4

Synthesis and evaluation of water-soluble non-prodrug analogs of docetaxel bearing sec-aminoethyl group at the C-10 position.

Uoto K, Takenoshita H, Yoshino T, Hirota Y, Ando S, Mitsui I, Terasawa H, Soga T. Uoto K, et al. Among authors: yoshino t. Chem Pharm Bull (Tokyo). 1998 May;46(5):770-6. doi: 10.1248/cpb.46.770. Chem Pharm Bull (Tokyo). 1998. PMID: 9621410

5

A new method for synthesis of 7-deoxytaxane analogues by hydrogenation of delta(6,7)-taxane derivatives.

Takeda Y, Yoshino T, Uoto K, Terasawa H, Soga T. Takeda Y, et al. Among authors: yoshino t. Chem Pharm Bull (Tokyo). 2002 Oct;50(10):1398-400. doi: 10.1248/cpb.50.1398. Chem Pharm Bull (Tokyo). 2002. PMID: 12372874 Free article.

6

Design, synthesis and SAR of novel ethylenediamine and phenylenediamine derivatives as factor Xa inhibitors.

Yoshikawa K, Yoshino T, Yokomizo Y, Uoto K, Naito H, Kawakami K, Mochizuki A, Nagata T, Suzuki M, Kanno H, Takemura M, Ohta T. Yoshikawa K, et al. Among authors: yoshino t. Bioorg Med Chem Lett. 2011 Apr 1;21(7):2133-40. doi: 10.1016/j.bmcl.2011.01.132. Epub 2011 Feb 1. Bioorg Med Chem Lett. 2011. PMID: 21345673

7

Design, synthesis, and biological activity of novel factor Xa inhibitors: improving metabolic stability by S1 and S4 ligand modification.

Komoriya S, Kobayashi S, Osanai K, Yoshino T, Nagata T, Haginoya N, Nakamoto Y, Mochizuki A, Nagahara T, Suzuki M, Shimada T, Watanabe K, Isobe Y, Furugoori T. Komoriya S, et al. Among authors: yoshino t. Bioorg Med Chem. 2006 Mar 1;14(5):1309-30. doi: 10.1016/j.bmc.2005.09.056. Epub 2005 Nov 2. Bioorg Med Chem. 2006. PMID: 16263291

8

Design, synthesis, and biological activity of non-basic compounds as factor Xa inhibitors: SAR study of S1 and aryl binding sites.

Komoriya S, Haginoya N, Kobayashi S, Nagata T, Mochizuki A, Suzuki M, Yoshino T, Horino H, Nagahara T, Suzuki M, Isobe Y, Furugoori T. Komoriya S, et al. Among authors: yoshino t. Bioorg Med Chem. 2005 Jun 2;13(12):3927-54. doi: 10.1016/j.bmc.2005.04.006. Bioorg Med Chem. 2005. PMID: 15911309

9

Discovery of N-[(1R,2S,5S)-2-{[(5-chloroindol-2-yl)carbonyl]amino}-5-(dimethylcarbamoyl)cyclohexyl]-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide hydrochloride: a novel, potent and orally active direct inhibitor of factor Xa.

Nagata T, Yoshino T, Haginoya N, Yoshikawa K, Nagamochi M, Kobayashi S, Komoriya S, Yokomizo A, Muto R, Yamaguchi M, Osanai K, Suzuki M, Kanno H. Nagata T, et al. Among authors: yoshino t. Bioorg Med Chem. 2009 Feb 1;17(3):1193-206. doi: 10.1016/j.bmc.2008.12.037. Epub 2008 Dec 24. Bioorg Med Chem. 2009. PMID: 19128974

10

Stereoselective synthesis and biological evaluation of 3,4-diaminocyclohexanecarboxylic acid derivatives as factor Xa inhibitors.

Nagata T, Nagamochi M, Kobayashi S, Komoriya S, Yoshino T, Kanno H. Nagata T, et al. Among authors: yoshino t. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4587-92. doi: 10.1016/j.bmcl.2008.07.031. Epub 2008 Jul 15. Bioorg Med Chem Lett. 2008. PMID: 18675545

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