McDonald AC - Search Results

1

Phase I and pharmacokinetic study of PKC412, an inhibitor of protein kinase C.

Propper DJ, McDonald AC, Man A, Thavasu P, Balkwill F, Braybrooke JP, Caponigro F, Graf P, Dutreix C, Blackie R, Kaye SB, Ganesan TS, Talbot DC, Harris AL, Twelves C. Propper DJ, et al. Among authors: mcdonald ac. J Clin Oncol. 2001 Mar 1;19(5):1485-92. doi: 10.1200/JCO.2001.19.5.1485. J Clin Oncol. 2001. PMID: 11230495 Clinical Trial.

2

A phase I and pharmacokinetic study of LY231514, the multitargeted antifolate.

McDonald AC, Vasey PA, Adams L, Walling J, Woodworth JR, Abrahams T, McCarthy S, Bailey NP, Siddiqui N, Lind MJ, Calvert AH, Twelves CJ, Cassidy J, Kaye SB. McDonald AC, et al. Clin Cancer Res. 1998 Mar;4(3):605-10. Clin Cancer Res. 1998. PMID: 9533527 Clinical Trial.

3

A phase I and pharmacokinetic study of capecitabine in combination with epirubicin and cisplatin in patients with inoperable oesophago-gastric adenocarcinoma.

Evans TR, Pentheroudakis G, Paul J, McInnes A, Blackie R, Raby N, Morrison R, Fullarton GM, Soukop M, McDonald AC. Evans TR, et al. Among authors: mcdonald ac. Ann Oncol. 2002 Sep;13(9):1469-78. doi: 10.1093/annonc/mdf243. Ann Oncol. 2002. PMID: 12196374 Free article. Clinical Trial.

4

Phase I/pharmacokinetic study of the topoisomerase I inhibitor GG211 administered as a 21-day continuous infusion.

Stevenson JP, DeMaria D, Sludden J, Kaye SB, Paz-Ares L, Grochow LB, McDonald A, Selinger K, Wissel P, O'Dwyer PJ, Twelves C. Stevenson JP, et al. Ann Oncol. 1999 Mar;10(3):339-44. doi: 10.1023/a:1008313011289. Ann Oncol. 1999. PMID: 10355580 Free article. Clinical Trial.

5

The protein kinase C inhibitor CGP41251 suppresses cytokine release and extracellular signal-regulated kinase 2 expression in cancer patients.

Thavasu P, Propper D, McDonald A, Dobbs N, Ganesan T, Talbot D, Braybrook J, Caponigro F, Hutchison C, Twelves C, Man A, Fabbro D, Harris A, Balkwill F. Thavasu P, et al. Cancer Res. 1999 Aug 15;59(16):3980-4. Cancer Res. 1999. PMID: 10463595 Clinical Trial.

6

A phase II study of epirubicin, cisplatin and raltitrexed combination chemotherapy (ECT) in patients with advanced oesophageal and gastric adenocarcinoma.

Mackay HJ, McInnes A, Paul J, Raby N, Lofts FJ, McDonald AC, Soukop M, Fullarton GM, Harris AL, Garcia-Vargas J, Evans TR. Mackay HJ, et al. Among authors: mcdonald ac. Ann Oncol. 2001 Oct;12(10):1407-10. doi: 10.1023/a:1012552823543. Ann Oncol. 2001. PMID: 11762812 Free article. Clinical Trial.

7

Phase I and pharmacokinetic study of tirapazamine (SR 4233) administered every three weeks.

Senan S, Rampling R, Graham MA, Wilson P, Robin H Jr, Eckardt N, Lawson N, McDonald A, von Roemeling R, Workman P, Kaye SB. Senan S, et al. Clin Cancer Res. 1997 Jan;3(1):31-8. Clin Cancer Res. 1997. PMID: 9815534 Clinical Trial.

8

A phase I and pharmacokinetic study of capecitabine in combination with radiotherapy in patients with localised inoperable pancreatic cancer.

Roxburgh P, Lumsden GR, Paul J, Harden S, Sweeting L, James A, Crellin A, Morrison R, Evans TR, McDonald AC. Roxburgh P, et al. Among authors: mcdonald ac. Cancer Chemother Pharmacol. 2014 Jul;74(1):131-9. doi: 10.1007/s00280-014-2470-4. Epub 2014 May 13. Cancer Chemother Pharmacol. 2014. PMID: 24819683 Clinical Trial.

9

A phase I dose escalation study of continuous oral capecitabine in combination with oxaliplatin and pelvic radiation (XELOX-RT) in patients with locally advanced rectal cancer.

Glynne-Jones R, Sebag-Montefiore D, Maughan TS, Falk SJ, McDonald AC. Glynne-Jones R, et al. Among authors: mcdonald ac. Ann Oncol. 2006 Jan;17(1):50-6. doi: 10.1093/annonc/mdj031. Epub 2005 Nov 10. Ann Oncol. 2006. PMID: 16284060 Free article. Clinical Trial.

10

Intermittent versus continuous oxaliplatin and fluoropyrimidine combination chemotherapy for first-line treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial.

Adams RA, Meade AM, Seymour MT, Wilson RH, Madi A, Fisher D, Kenny SL, Kay E, Hodgkinson E, Pope M, Rogers P, Wasan H, Falk S, Gollins S, Hickish T, Bessell EM, Propper D, Kennedy MJ, Kaplan R, Maughan TS; MRC COIN Trial Investigators. Adams RA, et al. Lancet Oncol. 2011 Jul;12(7):642-53. doi: 10.1016/S1470-2045(11)70102-4. Epub 2011 Jun 5. Lancet Oncol. 2011. PMID: 21641867 Free PMC article. Clinical Trial.

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