Lefkowitz RJ - Search Results

1

In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction.

Shah AS, White DC, Emani S, Kypson AP, Lilly RE, Wilson K, Glower DD, Lefkowitz RJ, Koch WJ. Shah AS, et al. Among authors: lefkowitz rj. Circulation. 2001 Mar 6;103(9):1311-6. doi: 10.1161/01.cir.103.9.1311. Circulation. 2001. PMID: 11238278

2

Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism.

Liggett SB, Ostrowski J, Chesnut LC, Kurose H, Raymond JR, Caron MG, Lefkowitz RJ. Liggett SB, et al. Among authors: lefkowitz rj. J Biol Chem. 1992 Mar 5;267(7):4740-6. J Biol Chem. 1992. PMID: 1311318 Free article.

3

Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors.

Pitcher JA, Inglese J, Higgins JB, Arriza JL, Casey PJ, Kim C, Benovic JL, Kwatra MM, Caron MG, Lefkowitz RJ. Pitcher JA, et al. Among authors: lefkowitz rj. Science. 1992 Aug 28;257(5074):1264-7. doi: 10.1126/science.1325672. Science. 1992. PMID: 1325672

4

G-protein-coupled receptors: regulatory role of receptor kinases and arrestin proteins.

Lefkowitz RJ, Inglese J, Koch WJ, Pitcher J, Attramadal H, Caron MG. Lefkowitz RJ, et al. Cold Spring Harb Symp Quant Biol. 1992;57:127-33. doi: 10.1101/sqb.1992.057.01.016. Cold Spring Harb Symp Quant Biol. 1992. PMID: 1339651 Review. No abstract available.

5

Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms.

Pitcher J, Lohse MJ, Codina J, Caron MG, Lefkowitz RJ. Pitcher J, et al. Among authors: lefkowitz rj. Biochemistry. 1992 Mar 31;31(12):3193-7. doi: 10.1021/bi00127a021. Biochemistry. 1992. PMID: 1348186

6

The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain.

Arriza JL, Dawson TM, Simerly RB, Martin LJ, Caron MG, Snyder SH, Lefkowitz RJ. Arriza JL, et al. Among authors: lefkowitz rj. J Neurosci. 1992 Oct;12(10):4045-55. doi: 10.1523/JNEUROSCI.12-10-04045.1992. J Neurosci. 1992. PMID: 1403099 Free PMC article.

7

Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases.

Inglese J, Koch WJ, Caron MG, Lefkowitz RJ. Inglese J, et al. Among authors: lefkowitz rj. Nature. 1992 Sep 10;359(6391):147-50. doi: 10.1038/359147a0. Nature. 1992. PMID: 1522899

8

Role of acidic amino acids in peptide substrates of the beta-adrenergic receptor kinase and rhodopsin kinase.

Onorato JJ, Palczewski K, Regan JW, Caron MG, Lefkowitz RJ, Benovic JL. Onorato JJ, et al. Among authors: lefkowitz rj. Biochemistry. 1991 May 28;30(21):5118-25. doi: 10.1021/bi00235a002. Biochemistry. 1991. PMID: 1645191

9

Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase.

Roth NS, Campbell PT, Caron MG, Lefkowitz RJ, Lohse MJ. Roth NS, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1991 Jul 15;88(14):6201-4. doi: 10.1073/pnas.88.14.6201. Proc Natl Acad Sci U S A. 1991. PMID: 1648731 Free PMC article.

10

The receptor kinase family: primary structure of rhodopsin kinase reveals similarities to the beta-adrenergic receptor kinase.

Lorenz W, Inglese J, Palczewski K, Onorato JJ, Caron MG, Lefkowitz RJ. Lorenz W, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1991 Oct 1;88(19):8715-9. doi: 10.1073/pnas.88.19.8715. Proc Natl Acad Sci U S A. 1991. PMID: 1656454 Free PMC article.

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