Sigal A - Search Results

1

Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53.

Seluanov A, Gorbunova V, Falcovitz A, Sigal A, Milyavsky M, Zurer I, Shohat G, Goldfinger N, Rotter V. Seluanov A, et al. Among authors: sigal a. Mol Cell Biol. 2001 Mar;21(5):1552-64. doi: 10.1128/MCB.21.5.1552-1564.2001. Mol Cell Biol. 2001. PMID: 11238892 Free PMC article.

2

Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome.

Sigal A, Rotter V. Sigal A, et al. Cancer Res. 2000 Dec 15;60(24):6788-93. Cancer Res. 2000. PMID: 11156366 Review.

3

The C-terminus of mutant p53 is necessary for its ability to interfere with growth arrest or apoptosis.

Sigal A, Matas D, Almog N, Goldfinger N, Rotter V. Sigal A, et al. Oncogene. 2001 Aug 9;20(35):4891-8. doi: 10.1038/sj.onc.1204724. Oncogene. 2001. PMID: 11521201

4

Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis.

Matas D, Sigal A, Stambolsky P, Milyavsky M, Weisz L, Schwartz D, Goldfinger N, Rotter V. Matas D, et al. Among authors: sigal a. EMBO J. 2001 Aug 1;20(15):4163-72. doi: 10.1093/emboj/20.15.4163. EMBO J. 2001. PMID: 11483519 Free PMC article.

5

Oscillations and variability in the p53 system.

Geva-Zatorsky N, Rosenfeld N, Itzkovitz S, Milo R, Sigal A, Dekel E, Yarnitzky T, Liron Y, Polak P, Lahav G, Alon U. Geva-Zatorsky N, et al. Among authors: sigal a. Mol Syst Biol. 2006;2:2006.0033. doi: 10.1038/msb4100068. Epub 2006 Jun 13. Mol Syst Biol. 2006. PMID: 16773083 Free PMC article.

6

Dynamics of the p53-Mdm2 feedback loop in individual cells.

Lahav G, Rosenfeld N, Sigal A, Geva-Zatorsky N, Levine AJ, Elowitz MB, Alon U. Lahav G, et al. Among authors: sigal a. Nat Genet. 2004 Feb;36(2):147-50. doi: 10.1038/ng1293. Epub 2004 Jan 18. Nat Genet. 2004. PMID: 14730303 Free article.

7

Dynamics and variability of ERK2 response to EGF in individual living cells.

Cohen-Saidon C, Cohen AA, Sigal A, Liron Y, Alon U. Cohen-Saidon C, et al. Among authors: sigal a. Mol Cell. 2009 Dec 11;36(5):885-93. doi: 10.1016/j.molcel.2009.11.025. Mol Cell. 2009. PMID: 20005850 Free article.

8

Dynamic proteomics of individual cancer cells in response to a drug.

Cohen AA, Geva-Zatorsky N, Eden E, Frenkel-Morgenstern M, Issaeva I, Sigal A, Milo R, Cohen-Saidon C, Liron Y, Kam Z, Cohen L, Danon T, Perzov N, Alon U. Cohen AA, et al. Among authors: sigal a. Science. 2008 Dec 5;322(5907):1511-6. doi: 10.1126/science.1160165. Epub 2008 Nov 20. Science. 2008. PMID: 19023046 Free article.

9

The LFA-1 integrin supports rolling adhesions on ICAM-1 under physiological shear flow in a permissive cellular environment.

Sigal A, Bleijs DA, Grabovsky V, van Vliet SJ, Dwir O, Figdor CG, van Kooyk Y, Alon R. Sigal A, et al. J Immunol. 2000 Jul 1;165(1):442-52. doi: 10.4049/jimmunol.165.1.442. J Immunol. 2000. PMID: 10861083

10

Variability and memory of protein levels in human cells.

Sigal A, Milo R, Cohen A, Geva-Zatorsky N, Klein Y, Liron Y, Rosenfeld N, Danon T, Perzov N, Alon U. Sigal A, et al. Nature. 2006 Nov 30;444(7119):643-6. doi: 10.1038/nature05316. Epub 2006 Nov 19. Nature. 2006. PMID: 17122776

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