Pinedo HM - Search Results

1

Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX-GA3 in combination with a monoclonal antibody beta-glucuronidase conjugate.

Houba PH, Boven E, van der Meulen-Muileman IH, Leenders RG, Scheeren JW, Pinedo HM, Haisma HJ. Houba PH, et al. Among authors: pinedo hm. Int J Cancer. 2001 Feb 15;91(4):550-4. doi: 10.1002/1097-0215(200002)9999:9999<::aid-ijc1075>3.0.co;2-l. Int J Cancer. 2001. PMID: 11251980

2

Pronounced antitumor efficacy by extracellular activation of a doxorubicin-glucuronide prodrug after adenoviral vector-mediated expression of a human antibody-enzyme fusion protein.

de Graaf M, Pinedo HM, Oosterhoff D, van der Meulen-Muileman IH, Gerritsen WR, Haisma HJ, Boven E. de Graaf M, et al. Among authors: pinedo hm. Hum Gene Ther. 2004 Mar;15(3):229-38. doi: 10.1089/104303404322886084. Hum Gene Ther. 2004. PMID: 15018732

3

A methylester of the glucuronide prodrug DOX-GA3 for improvement of tumor-selective chemotherapy.

de Graaf M, Nevalainen TJ, Scheeren HW, Pinedo HM, Haisma HJ, Boven E. de Graaf M, et al. Among authors: pinedo hm. Biochem Pharmacol. 2004 Dec 1;68(11):2273-81. doi: 10.1016/j.bcp.2004.08.004. Biochem Pharmacol. 2004. PMID: 15498517

4

Beta-glucuronidase-mediated drug release.

de Graaf M, Boven E, Scheeren HW, Haisma HJ, Pinedo HM. de Graaf M, et al. Among authors: pinedo hm. Curr Pharm Des. 2002;8(15):1391-403. doi: 10.2174/1381612023394485. Curr Pharm Des. 2002. PMID: 12052215 Review.

5

Novel camptothecin derivative BNP1350 in experimental human ovarian cancer: determination of efficacy and possible mechanisms of resistance.

Van Hattum AH, Schlüper HM, Hausheer FH, Pinedo HM, Boven E. Van Hattum AH, et al. Among authors: pinedo hm. Int J Cancer. 2002 Jul 1;100(1):22-9. doi: 10.1002/ijc.10434. Int J Cancer. 2002. PMID: 12115582

6

Influence of dose and schedule on the therapeutic efficacy of 131I-labelled monoclonal antibody 139H2 in a human ovarian cancer xenograft model.

Molthoff CF, Pinedo HM, Schlüper HM, Boven E. Molthoff CF, et al. Among authors: pinedo hm. Int J Cancer. 1992 Feb 1;50(3):474-80. doi: 10.1002/ijc.2910500324. Int J Cancer. 1992. PMID: 1735615

7

The effects of gamma-interferon combined with 5-fluorouracil or 5-fluoro-2'-deoxyuridine on proliferation and antigen expression in a panel of human colorectal cancer cell lines.

Maas IW, Boven E, Pinedo HM, Schlüper HM, Haisma HJ. Maas IW, et al. Among authors: pinedo hm. Int J Cancer. 1991 Jul 9;48(5):749-56. doi: 10.1002/ijc.2910480520. Int J Cancer. 1991. PMID: 1830034

8

Human ovarian cancer xenografts in nude mice: characterization and analysis of antigen expression.

Molthoff CF, Calame JJ, Pinedo HM, Boven E. Molthoff CF, et al. Among authors: pinedo hm. Int J Cancer. 1991 Jan 2;47(1):72-9. doi: 10.1002/ijc.2910470114. Int J Cancer. 1991. PMID: 1985883

9

Doxorubicin compared with related compounds in a nude mouse model for human ovarian cancer.

Boven E, Schlüper HM, Erkelens CA, Pinedo HM. Boven E, et al. Among authors: pinedo hm. Eur J Cancer. 1990;26(9):983-6. doi: 10.1016/0277-5379(90)90626-5. Eur J Cancer. 1990. PMID: 2149026

10

Comparison of two anthracycline-based prodrugs for activation by a monoclonal antibody-beta-glucuronidase conjugate in the specific treatment of cancer.

Haisma HJ, van Muijen M, Pinedo HM, Boven E. Haisma HJ, et al. Among authors: pinedo hm. Cell Biophys. 1994;24-25:185-92. doi: 10.1007/BF02789229. Cell Biophys. 1994. PMID: 7736523

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