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Enhanced therapeutic index of radioimmunotherapy (RIT) in prostate cancer patients: comparison of radiation dosimetry for 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid (DOTA)-peptide versus 2IT-DOTA monoclonal antibody linkage for RIT.
DeNardo SJ, DeNardo GL, Yuan A, Richman CM, O'Donnell RT, Lara PN, Kukis DL, Natarajan A, Lamborn KR, Jacobs F, Siantar CL. DeNardo SJ, et al. Among authors: kukis dl. Clin Cancer Res. 2003 Sep 1;9(10 Pt 2):3938S-44S. Clin Cancer Res. 2003. PMID: 14506192
High-dose radioimmunotherapy combined with fixed, low-dose paclitaxel in metastatic prostate and breast cancer by using a MUC-1 monoclonal antibody, m170, linked to indium-111/yttrium-90 via a cathepsin cleavable linker with cyclosporine to prevent human anti-mouse antibody.
Richman CM, Denardo SJ, O'Donnell RT, Yuan A, Shen S, Goldstein DS, Tuscano JM, Wun T, Chew HK, Lara PN, Kukis DL, Natarajan A, Meares CF, Lamborn KR, DeNardo GL. Richman CM, et al. Among authors: kukis dl. Clin Cancer Res. 2005 Aug 15;11(16):5920-7. doi: 10.1158/1078-0432.CCR-05-0211. Clin Cancer Res. 2005. PMID: 16115934 Clinical Trial.
56 results