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Lack of correlation between in vitro inhibition of CYP3A-mediated metabolism by a PPAR-gamma agonist and its effect on the clinical pharmacokinetics of midazolam, an in vivo probe of CYP3A activity.
J Clin Pharmacol. 2001 Mar;41(3):305-16. doi: 10.1177/00912700122010122.
J Clin Pharmacol. 2001.
PMID: 11269571
Clinical Trial.
Characterization of 2-[[4-[[2-(1H-tetrazol-5-ylmethyl)phenyl]methoxy]methyl]quinoline N-glucuronidation by in vitro and in vivo approaches.
Stevens JC, Fayer JL, Cassidy KC.
Stevens JC, et al. Among authors: fayer jl.
Drug Metab Dispos. 2001 Mar;29(3):289-95.
Drug Metab Dispos. 2001.
PMID: 11181497
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A novel testosterone 6 beta-hydroxylase activity assay for the study of CYP3A-mediated metabolism, inhibition, and induction in vitro.
Fayer JL, Petullo DM, Ring BJ, Wrighton SA, Ruterbories KJ.
Fayer JL, et al.
J Pharmacol Toxicol Methods. 2001 Sep-Oct;46(2):117-23. doi: 10.1016/s1056-8719(02)00168-5.
J Pharmacol Toxicol Methods. 2001.
PMID: 12481849
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