Timmerman H - Search Results

1

Synthesis and use of FSCPX, an irreversible adenosine A1 antagonist, as a 'receptor knock-down' tool.

van Muijlwijk-Koezen JE, Timmerman H, van der Sluis RP, van de Stolpe AC, Menge WM, Beukers MW, van der Graaf PH, de Groote M, IJzerman AP. van Muijlwijk-Koezen JE, et al. Among authors: timmerman h. Bioorg Med Chem Lett. 2001 Mar 26;11(6):815-8. doi: 10.1016/s0960-894x(01)00069-5. Bioorg Med Chem Lett. 2001. PMID: 11277527

2

Synthesis and structure-activity relationships of carboxyflavones as structurally rigid CysLT1 (LTD4) receptor antagonists.

Zwaagstra ME, Timmerman H, van de Stolpe AC, de Kanter FJ, Tamura M, Wada Y, Zhang MQ. Zwaagstra ME, et al. Among authors: timmerman h. J Med Chem. 1998 Apr 23;41(9):1428-38. doi: 10.1021/jm970179x. J Med Chem. 1998. PMID: 9554876

3

A novel class of adenosine A3 receptor ligands. 1. 3-(2-Pyridinyl)isoquinoline derivatives.

van Muijlwijk-Koezen JE, Timmerman H, Link R, van der Goot H, IJzerman AP. van Muijlwijk-Koezen JE, et al. Among authors: timmerman h. J Med Chem. 1998 Oct 8;41(21):3987-93. doi: 10.1021/jm980036q. J Med Chem. 1998. PMID: 9767636

4

A novel class of adenosine A3 receptor ligands. 2. Structure affinity profile of a series of isoquinoline and quinazoline compounds.

van Muijlwijk-Koezen JE, Timmerman H, Link R, van der Goot H, Ijzerman AP. van Muijlwijk-Koezen JE, et al. Among authors: timmerman h. J Med Chem. 1998 Oct 8;41(21):3994-4000. doi: 10.1021/jm980037i. J Med Chem. 1998. PMID: 9767637

5

Synthesis and histamine H3 receptor activity of 4-(n-alkyl)-1H-imidazoles and 4-(omega-phenylalkyl)-1H-imidazoles.

De Esch IJ, Gaffar A, Menge WM, Timmerman H. De Esch IJ, et al. Among authors: timmerman h. Bioorg Med Chem. 1999 Dec;7(12):3003-9. doi: 10.1016/s0968-0896(99)00253-9. Bioorg Med Chem. 1999. PMID: 10658607

6

Isoquinoline and quinazoline urea analogues as antagonists for the human adenosine A(3) receptor.

van Muijlwijk-Koezen JE, Timmerman H, van der Goot H, Menge WM, Frijtag Von Drabbe Künzel J, de Groote M, IJzerman AP. van Muijlwijk-Koezen JE, et al. Among authors: timmerman h. J Med Chem. 2000 Jun 1;43(11):2227-38. doi: 10.1021/jm000002u. J Med Chem. 2000. PMID: 10841801 Free article.

7

Solid-phase synthesis of 4-substituted imidazoles using a scaffold approach.

Gelens E, Koot WJ, Menge WM, Ottenheijm HC, Timmerman H. Gelens E, et al. Among authors: timmerman h. Bioorg Med Chem Lett. 2000 Sep 4;10(17):1935-8. doi: 10.1016/s0960-894x(00)00363-2. Bioorg Med Chem Lett. 2000. PMID: 10987421

8

Thiazole and thiadiazole analogues as a novel class of adenosine receptor antagonists.

van Muijlwijk-Koezen JE, Timmerman H, Vollinga RC, Frijtag von Drabbe Künzel J, de Groote M, Visser S, IJzerman AP. van Muijlwijk-Koezen JE, et al. Among authors: timmerman h. J Med Chem. 2001 Mar 1;44(5):749-62. doi: 10.1021/jm0003945. J Med Chem. 2001. PMID: 11262085

9

The adenosine A3 receptor and its ligands.

van Muijlwijk-Koezen JE, Timmerman H, Ijzerman AP. van Muijlwijk-Koezen JE, et al. Among authors: timmerman h. Prog Med Chem. 2001;38:61-113. doi: 10.1016/s0079-6468(08)70092-4. Prog Med Chem. 2001. PMID: 11774799 Review. No abstract available.

10

New analogs of burimamide as potent and selective histamine H3 receptor antagonists: the effect of chain length variation of the alkyl spacer and modifications of the N-thiourea substituent.

Vollinga RC, Menge WM, Leurs R, Timmerman H. Vollinga RC, et al. Among authors: timmerman h. J Med Chem. 1995 Jun 9;38(12):2244-50. doi: 10.1021/jm00012a025. J Med Chem. 1995. PMID: 7783156

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