Tekmal RR - Search Results

1

Overexpression of aromatase leads to hyperplasia and changes in the expression of genes involved in apoptosis, cell cycle, growth, and tumor suppressor functions in the mammary glands of transgenic mice.

Kirma N, Gill K, Mandava U, Tekmal RR. Kirma N, et al. Among authors: tekmal rr. Cancer Res. 2001 Mar 1;61(5):1910-8. Cancer Res. 2001. PMID: 11280746

2

Preclinical Development of Brain Permeable ERβ Agonist for the Treatment of Glioblastoma.

Pratap UP, Tidwell M, Balinda HU, Clanton NA, Yang X, Viswanadhapalli S, Sareddy GR, Liang D, Xie H, Chen Y, Lai Z, Tekmal RR, McHardy SF, Brenner AJ, Vadlamudi RK. Pratap UP, et al. Among authors: tekmal rr. Mol Cancer Ther. 2023 Nov 1;22(11):1248-1260. doi: 10.1158/1535-7163.MCT-23-0031. Mol Cancer Ther. 2023. PMID: 37493258 Free PMC article.

3

Inhibition of LIFR Blocks Adiposity-Driven Endometrioid Endometrial Cancer Growth.

Blankenship L, Pratap UP, Yang X, Liu Z, Altwegg KA, Santhamma B, Ramasamy K, Konda S, Chen Y, Lai Z, Zheng S, Sareddy GR, Valente PT, Kost ER, Nair HB, Tekmal RR, Vadlamudi RK, Viswanadhapalli S. Blankenship L, et al. Among authors: tekmal rr. Cancers (Basel). 2022 Nov 2;14(21):5400. doi: 10.3390/cancers14215400. Cancers (Basel). 2022. PMID: 36358818 Free PMC article.

4

The nature and expression of int-5, a novel MMTV integration locus gene in carcinogen-induced mammary tumors.

Durgam VR, Tekmal RR. Durgam VR, et al. Among authors: tekmal rr. Cancer Lett. 1994 Dec 9;87(2):179-86. doi: 10.1016/0304-3835(94)90220-8. Cancer Lett. 1994. PMID: 7812938

5

The overexpression of int-5/Aromatase, a novel MMTV integration locus gene, is responsible for D2 mammary tumor cell proliferation.

Tekmal RR, Durgam VR. Tekmal RR, et al. Cancer Lett. 1995 Jan 27;88(2):147-55. doi: 10.1016/0304-3835(94)03630-2. Cancer Lett. 1995. PMID: 7874687

6

Overexpression of int-5/aromatase in mammary glands of transgenic mice results in the induction of hyperplasia and nuclear abnormalities.

Tekmal RR, Ramachandra N, Gubba S, Durgam VR, Mantione J, Toda K, Shizuta Y, Dillehay DL. Tekmal RR, et al. Cancer Res. 1996 Jul 15;56(14):3180-5. Cancer Res. 1996. PMID: 8764102

7

A novel in vitro and in vivo breast cancer model for testing inhibitors of estrogen biosynthesis and its action using mammary tumor cells with an activated int-5/aromatase gene.

Tekmal RR, Durgam VR. Tekmal RR, et al. Cancer Lett. 1997 Sep 16;118(1):21-8. doi: 10.1016/s0304-3835(97)00219-x. Cancer Lett. 1997. PMID: 9310256

8

Overexpression of macrophage colony-stimulating factor (CSF-1) and its receptor, c-fms, in normal ovarian granulosa cells leads to cell proliferation and tumorigenesis.

Keshava N, Gubba S, Tekmal RR. Keshava N, et al. Among authors: tekmal rr. J Soc Gynecol Investig. 1999 Jan-Feb;6(1):41-9. J Soc Gynecol Investig. 1999. PMID: 10065425

9

Overexpression of aromatase leads to development of testicular leydig cell tumors : an in vivo model for hormone-mediated TesticularCancer.

Fowler KA, Gill K, Kirma N, Dillehay DL, Tekmal RR. Fowler KA, et al. Among authors: tekmal rr. Am J Pathol. 2000 Jan;156(1):347-53. doi: 10.1016/S0002-9440(10)64736-0. Am J Pathol. 2000. PMID: 10623684 Free PMC article.

10

Aromatase overexpression and breast hyperplasia, an in vivo model--continued overexpression of aromatase is sufficient to maintain hyperplasia without circulating estrogens, and aromatase inhibitors abrogate these preneoplastic changes in mammary glands.

Tekmal RR, Kirma N, Gill K, Fowler K. Tekmal RR, et al. Endocr Relat Cancer. 1999 Jun;6(2):307-14. doi: 10.1677/erc.0.0060307. Endocr Relat Cancer. 1999. PMID: 10731124

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