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Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies.
Desreumaux P, Dubuquoy L, Nutten S, Peuchmaur M, Englaro W, Schoonjans K, Derijard B, Desvergne B, Wahli W, Chambon P, Leibowitz MD, Colombel JF, Auwerx J. Desreumaux P, et al. Among authors: desvergne b. J Exp Med. 2001 Apr 2;193(7):827-38. doi: 10.1084/jem.193.7.827. J Exp Med. 2001. PMID: 11283155 Free PMC article.
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma.
Rousseaux C, Lefebvre B, Dubuquoy L, Lefebvre P, Romano O, Auwerx J, Metzger D, Wahli W, Desvergne B, Naccari GC, Chavatte P, Farce A, Bulois P, Cortot A, Colombel JF, Desreumaux P. Rousseaux C, et al. Among authors: desvergne b. J Exp Med. 2005 Apr 18;201(8):1205-15. doi: 10.1084/jem.20041948. Epub 2005 Apr 11. J Exp Med. 2005. PMID: 15824083 Free PMC article.
Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon.
Peyrin-Biroulet L, Beisner J, Wang G, Nuding S, Oommen ST, Kelly D, Parmentier-Decrucq E, Dessein R, Merour E, Chavatte P, Grandjean T, Bressenot A, Desreumaux P, Colombel JF, Desvergne B, Stange EF, Wehkamp J, Chamaillard M. Peyrin-Biroulet L, et al. Among authors: desvergne b. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8772-7. doi: 10.1073/pnas.0905745107. Epub 2010 Apr 26. Proc Natl Acad Sci U S A. 2010. PMID: 20421464 Free PMC article.
150 results