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Progress toward the development of a safe and effective agent for treating reentrant cardiac arrhythmias: synthesis and evaluation of ibutilide analogues with enhanced metabolic stability and diminished proarrhythmic potential.
Hester JB, Gibson JK, Buchanan LV, Cimini MG, Clark MA, Emmert DE, Glavanovich MA, Imbordino RJ, LeMay RJ, McMillan MW, Perricone SC, Squires DM, Walters RR. Hester JB, et al. Among authors: emmert de. J Med Chem. 2001 Mar 29;44(7):1099-115. doi: 10.1021/jm0004289. J Med Chem. 2001. PMID: 11297456
Nitrogen-carbon-linked (azolylphenyl)oxazolidinones with potent antibacterial activity against the fastidious gram-negative organisms Haemophilus influenzae and Moraxella catarrhalis.
Genin MJ, Hutchinson DK, Allwine DA, Hester JB, Emmert DE, Garmon SA, Ford CW, Zurenko GE, Hamel JC, Schaadt RD, Stapert D, Yagi BH, Friis JM, Shobe EM, Adams WJ. Genin MJ, et al. Among authors: emmert de. J Med Chem. 1998 Dec 17;41(26):5144-7. doi: 10.1021/jm980546k. J Med Chem. 1998. PMID: 9857083 No abstract available.
Substituent effects on the antibacterial activity of nitrogen-carbon-linked (azolylphenyl)oxazolidinones with expanded activity against the fastidious gram-negative organisms Haemophilus influenzae and Moraxella catarrhalis.
Genin MJ, Allwine DA, Anderson DJ, Barbachyn MR, Emmert DE, Garmon SA, Graber DR, Grega KC, Hester JB, Hutchinson DK, Morris J, Reischer RJ, Ford CW, Zurenko GE, Hamel JC, Schaadt RD, Stapert D, Yagi BH. Genin MJ, et al. Among authors: emmert de. J Med Chem. 2000 Mar 9;43(5):953-70. doi: 10.1021/jm990373e. J Med Chem. 2000. PMID: 10715160
26 results