Moore JT - Search Results

1

Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha.

Spencer TA, Li D, Russel JS, Collins JL, Bledsoe RK, Consler TG, Moore LB, Galardi CM, McKee DD, Moore JT, Watson MA, Parks DJ, Lambert MH, Willson TM. Spencer TA, et al. Among authors: moore lb, moore jt. J Med Chem. 2001 Mar 15;44(6):886-97. doi: 10.1021/jm0004749. J Med Chem. 2001. PMID: 11300870

2

X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by a histidine-tryptophan switch.

Williams S, Bledsoe RK, Collins JL, Boggs S, Lambert MH, Miller AB, Moore J, McKee DD, Moore L, Nichols J, Parks D, Watson M, Wisely B, Willson TM. Williams S, et al. J Biol Chem. 2003 Jul 18;278(29):27138-43. doi: 10.1074/jbc.M302260200. Epub 2003 May 7. J Biol Chem. 2003. PMID: 12736258 Free article.

3

A new series of estrogen receptor modulators that display selectivity for estrogen receptor beta.

Henke BR, Consler TG, Go N, Hale RL, Hohman DR, Jones SA, Lu AT, Moore LB, Moore JT, Orband-Miller LA, Robinett RG, Shearin J, Spearing PK, Stewart EL, Turnbull PS, Weaver SL, Williams SP, Wisely GB, Lambert MH. Henke BR, et al. Among authors: moore lb, moore jt. J Med Chem. 2002 Dec 5;45(25):5492-505. doi: 10.1021/jm020291h. J Med Chem. 2002. PMID: 12459017

4

Discovery of tertiary sulfonamides as potent liver X receptor antagonists.

Zuercher WJ, Buckholz RG, Campobasso N, Collins JL, Galardi CM, Gampe RT, Hyatt SM, Merrihew SL, Moore JT, Oplinger JA, Reid PR, Spearing PK, Stanley TB, Stewart EL, Willson TM. Zuercher WJ, et al. Among authors: moore jt. J Med Chem. 2010 Apr 22;53(8):3412-6. doi: 10.1021/jm901797p. J Med Chem. 2010. PMID: 20345102

5

Chemical genomics: functional analysis of orphan nuclear receptors in the regulation of bile acid metabolism.

Willson TM, Jones SA, Moore JT, Kliewer SA. Willson TM, et al. Among authors: moore jt. Med Res Rev. 2001 Nov;21(6):513-22. doi: 10.1002/med.1023. Med Res Rev. 2001. PMID: 11607932 Review.

6

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha.

Xu HE, Stanley TB, Montana VG, Lambert MH, Shearer BG, Cobb JE, McKee DD, Galardi CM, Plunket KD, Nolte RT, Parks DJ, Moore JT, Kliewer SA, Willson TM, Stimmel JB. Xu HE, et al. Among authors: moore jt. Nature. 2002 Feb 14;415(6873):813-7. doi: 10.1038/415813a. Nature. 2002. PMID: 11845213

7

Genomics versus orphan nuclear receptors--a half-time report.

Willson TM, Moore JT. Willson TM, et al. Among authors: moore jt. Mol Endocrinol. 2002 Jun;16(6):1135-44. doi: 10.1210/mend.16.6.0849. Mol Endocrinol. 2002. PMID: 12040002 Review.

8

Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition.

Bledsoe RK, Montana VG, Stanley TB, Delves CJ, Apolito CJ, McKee DD, Consler TG, Parks DJ, Stewart EL, Willson TM, Lambert MH, Moore JT, Pearce KH, Xu HE. Bledsoe RK, et al. Among authors: moore jt. Cell. 2002 Jul 12;110(1):93-105. doi: 10.1016/s0092-8674(02)00817-6. Cell. 2002. PMID: 12151000 Free article.

9

Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes.

Maglich JM, Parks DJ, Moore LB, Collins JL, Goodwin B, Billin AN, Stoltz CA, Kliewer SA, Lambert MH, Willson TM, Moore JT. Maglich JM, et al. Among authors: moore lb, moore jt. J Biol Chem. 2003 May 9;278(19):17277-83. doi: 10.1074/jbc.M300138200. Epub 2003 Feb 27. J Biol Chem. 2003. PMID: 12611900 Free article.

10

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway.

Kliewer SA, Moore JT, Wade L, Staudinger JL, Watson MA, Jones SA, McKee DD, Oliver BB, Willson TM, Zetterström RH, Perlmann T, Lehmann JM. Kliewer SA, et al. Among authors: moore jt. Cell. 1998 Jan 9;92(1):73-82. doi: 10.1016/s0092-8674(00)80900-9. Cell. 1998. PMID: 9489701 Free article.

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