Ficker E - Search Results

1

High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872.

Thomas D, Wendt-Nordahl G, Röckl K, Ficker E, Brown AM, Kiehn J. Thomas D, et al. Among authors: ficker e. J Pharmacol Exp Ther. 2001 May;297(2):753-61. J Pharmacol Exp Ther. 2001. PMID: 11303067

2

Inhibition of human ether-a-go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin.

Thomas D, Wimmer AB, Wu K, Hammerling BC, Ficker EK, Kuryshev YA, Kiehn J, Katus HA, Schoels W, Karle CA. Thomas D, et al. Naunyn Schmiedebergs Arch Pharmacol. 2004 May;369(5):462-72. doi: 10.1007/s00210-004-0931-8. Epub 2004 Apr 20. Naunyn Schmiedebergs Arch Pharmacol. 2004. PMID: 15098086

3

Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action.

Thomas D, Hammerling BC, Wu K, Wimmer AB, Ficker EK, Kirsch GE, Kochan MC, Wible BA, Scholz EP, Zitron E, Kathöfer S, Kreye VA, Katus HA, Schoels W, Karle CA, Kiehn J. Thomas D, et al. Among authors: ficker ek. Br J Pharmacol. 2004 Jun;142(3):485-94. doi: 10.1038/sj.bjp.0705795. Epub 2004 May 17. Br J Pharmacol. 2004. PMID: 15148258 Free PMC article.

4

Protein kinase A-mediated phosphorylation of HERG potassium channels in a human cell line.

Wei Z, Thomas D, Karle CA, Kathöfer S, Schenkel J, Kreye VA, Ficker E, Wible BA, Kiehn J. Wei Z, et al. Among authors: ficker e. Chin Med J (Engl). 2002 May;115(5):668-76. Chin Med J (Engl). 2002. PMID: 12133532

5

Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels.

Ficker E, Jarolimek W, Brown AM. Ficker E, et al. Mol Pharmacol. 2001 Dec;60(6):1343-8. doi: 10.1124/mol.60.6.1343. Mol Pharmacol. 2001. PMID: 11723241

6

Direct block of hERG potassium channels by the protein kinase C inhibitor bisindolylmaleimide I (GF109203X).

Thomas D, Hammerling BC, Wimmer AB, Wu K, Ficker E, Kuryshev YA, Scherer D, Kiehn J, Katus HA, Schoels W, Karle CA. Thomas D, et al. Among authors: ficker e. Cardiovasc Res. 2004 Dec 1;64(3):467-76. doi: 10.1016/j.cardiores.2004.07.023. Cardiovasc Res. 2004. PMID: 15537500

7

The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations.

Ficker E, Obejero-Paz CA, Zhao S, Brown AM. Ficker E, et al. J Biol Chem. 2002 Feb 15;277(7):4989-98. doi: 10.1074/jbc.M107345200. Epub 2001 Dec 10. J Biol Chem. 2002. PMID: 11741928 Free article.

8

Doxazosin induces apoptosis of cells expressing hERG K+ channels.

Thomas D, Bloehs R, Koschny R, Ficker E, Sykora J, Kiehn J, Schlömer K, Gierten J, Kathöfer S, Zitron E, Scholz EP, Kiesecker C, Katus HA, Karle CA. Thomas D, et al. Among authors: ficker e. Eur J Pharmacol. 2008 Jan 28;579(1-3):98-103. doi: 10.1016/j.ejphar.2007.10.051. Epub 2007 Dec 4. Eur J Pharmacol. 2008. PMID: 18054910 Free PMC article.

9

The human cardiac K2P3.1 (TASK-1) potassium leak channel is a molecular target for the class III antiarrhythmic drug amiodarone.

Gierten J, Ficker E, Bloehs R, Schweizer PA, Zitron E, Scholz E, Karle C, Katus HA, Thomas D. Gierten J, et al. Among authors: ficker e. Naunyn Schmiedebergs Arch Pharmacol. 2010 Mar;381(3):261-70. doi: 10.1007/s00210-009-0454-4. Epub 2009 Sep 24. Naunyn Schmiedebergs Arch Pharmacol. 2010. PMID: 19777211

10

Cloned human inward rectifier K+ channel as a target for class III methanesulfonanilides.

Kiehn J, Wible B, Ficker E, Taglialatela M, Brown AM. Kiehn J, et al. Among authors: ficker e. Circ Res. 1995 Dec;77(6):1151-5. doi: 10.1161/01.res.77.6.1151. Circ Res. 1995. PMID: 7586228

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