Cook PD - Search Results

1

Synthesis of novel 3'-C-methylene thymidine and 5-methyluridine/cytidine H-phosphonates and phosphonamidites for new backbone modification of oligonucleotides.

An H, Wang T, Maier MA, Manoharan M, Ross BS, Cook PD. An H, et al. Among authors: cook pd. J Org Chem. 2001 Apr 20;66(8):2789-801. doi: 10.1021/jo001699u. J Org Chem. 2001. PMID: 11304203

2

Chimeric RNA with modified backbones: alternating methylene(methylimino) linked phosphodiester backbone oligonucleotides with 2'-OH and 2'-OMe groups.

Prhavc M, Bhat B, Just G, Cook PD, Manoharan M. Prhavc M, et al. Among authors: cook pd. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):995-7. doi: 10.1081/NCN-100002476. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11563162

3

2'-O-[2-[2-(N,N-dimethylamino)ethoxy]ethyl] modified oligonucleotides: symbiosis of charge interaction factors and stereoelectronic effects.

Prhavc M, Prakash TP, Minasov G, Cook PD, Egli M, Manoharan M. Prhavc M, et al. Among authors: cook pd. Org Lett. 2003 Jun 12;5(12):2017-20. doi: 10.1021/ol0340991. Org Lett. 2003. PMID: 12790517

4

Discovery of novel pyridinopolyamines with potent antimicrobial activity: deconvolution of mixtures synthesized by solution-phase combinatorial chemistry.

An H, Haly BD, Cook PD. An H, et al. Among authors: cook pd. J Med Chem. 1998 Feb 26;41(5):706-16. doi: 10.1021/jm970598u. J Med Chem. 1998. PMID: 9513599

5

New piperazinyl polyazacyclophane scaffolds, libraries and biological activities.

An H, Haly BD, Cook PD. An H, et al. Among authors: cook pd. Bioorg Med Chem Lett. 1998 Sep 8;8(17):2345-50. doi: 10.1016/s0960-894x(98)00424-7. Bioorg Med Chem Lett. 1998. PMID: 9873539

6

Site-specific cross-linking of nucleic acids using the abasic site.

Manoharan M, Andrade LK, Cook PD. Manoharan M, et al. Among authors: cook pd. Org Lett. 1999 Jul 29;1(2):311-4. doi: 10.1021/ol9906209. Org Lett. 1999. PMID: 10822568

7

Methodologies for Generating Solution-Phase Combinatorial Libraries.

An H, Cook PD. An H, et al. Among authors: cook pd. Chem Rev. 2000 Sep 15;100(9):3311-3340. doi: 10.1021/cr990014r. Chem Rev. 2000. PMID: 11777426 No abstract available.

8

MMI linkage modification increases potency and stability of H-ras antisense oligonucleotides.

Cowsert LM, Ohashi CT, Bhat B, Peoc'h D, Symons AM, Cook PD, Manoharan M. Cowsert LM, et al. Among authors: cook pd. Nucleosides Nucleotides. 1999 Jun-Jul;18(6-7):1383-4. doi: 10.1080/07328319908044723. Nucleosides Nucleotides. 1999. PMID: 10474224 No abstract available.

9

A 2'-O-thiol tether in the ribose moiety of nucleic acids for conjugation chemistry.

Manoharan M, Tivel KL, Ross B, Cook PD. Manoharan M, et al. Among authors: cook pd. Gene. 1994 Nov 4;149(1):147-56. doi: 10.1016/0378-1119(94)90423-5. Gene. 1994. PMID: 7958979

10

Synthesis and electrochemistry of anthraquinone-oligodeoxynucleotide conjugates.

Whittemore NA, Mullenix AN, Inamati GB, Manoharan M, Cook PD, Tuinman AA, Baker DC, Chambers JQ. Whittemore NA, et al. Among authors: cook pd. Bioconjug Chem. 1999 Mar-Apr;10(2):261-70. doi: 10.1021/bc980095i. Bioconjug Chem. 1999. PMID: 10077476

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