Ross BS - Search Results

1

Synthesis of novel 3'-C-methylene thymidine and 5-methyluridine/cytidine H-phosphonates and phosphonamidites for new backbone modification of oligonucleotides.

An H, Wang T, Maier MA, Manoharan M, Ross BS, Cook PD. An H, et al. Among authors: ross bs. J Org Chem. 2001 Apr 20;66(8):2789-801. doi: 10.1021/jo001699u. J Org Chem. 2001. PMID: 11304203

2

Comparing in vitro and in vivo activity of 2'-O-[2-(methylamino)-2-oxoethyl]- and 2'-O-methoxyethyl-modified antisense oligonucleotides.

Prakash TP, Kawasaki AM, Wancewicz EV, Shen L, Monia BP, Ross BS, Bhat B, Manoharan M. Prakash TP, et al. Among authors: ross bs. J Med Chem. 2008 May 8;51(9):2766-76. doi: 10.1021/jm701537z. Epub 2008 Apr 10. J Med Chem. 2008. PMID: 18399648

3

A Chemical Approach to Introduce 2,6-Diaminopurine and 2-Aminoadenine Conjugates into Oligonucleotides without Need for Protecting Groups.

Madaoui M, Datta D, Wassarman K, Zlatev I, Egli M, Ross BS, Manoharan M. Madaoui M, et al. Among authors: ross bs. Org Lett. 2022 Aug 26;24(33):6111-6116. doi: 10.1021/acs.orglett.2c01848. Epub 2022 Aug 16. Org Lett. 2022. PMID: 35973215 Free PMC article.

4

Evaluation of C-5 propynyl pyrimidine-containing oligonucleotides in vitro and in vivo.

Shen L, Siwkowski A, Wancewicz EV, Lesnik E, Butler M, Witchell D, Vasquez G, Ross B, Acevedo O, Inamati G, Sasmor H, Manoharan M, Monia BP. Shen L, et al. Antisense Nucleic Acid Drug Dev. 2003;13(3):129-42. doi: 10.1089/108729003768247592. Antisense Nucleic Acid Drug Dev. 2003. PMID: 12954113

5

A 2'-O-thiol tether in the ribose moiety of nucleic acids for conjugation chemistry.

Manoharan M, Tivel KL, Ross B, Cook PD. Manoharan M, et al. Gene. 1994 Nov 4;149(1):147-56. doi: 10.1016/0378-1119(94)90423-5. Gene. 1994. PMID: 7958979

6

Investigation of the proposed interdomain ribose zipper in hairpin ribozyme cleavage using 2'-modified nucleosides.

Earnshaw DJ, Hamm ML, Piccirilli JA, Karpeisky A, Beigelman L, Ross BS, Manoharan M, Gait MJ. Earnshaw DJ, et al. Among authors: ross bs. Biochemistry. 2000 May 30;39(21):6410-21. doi: 10.1021/bi992974d. Biochemistry. 2000. PMID: 10828955

7

Kilo-scale synthesis process for 2'-O-(2-methoxyethyl)-pyrimidine derivatives.

Ross BS, Song Q, Han M. Ross BS, et al. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):815-8. doi: 10.1081/ncn-200060295. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16248042

8

Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2'-O-ribonucleic acid modifications.

Egli M, Minasov G, Tereshko V, Pallan PS, Teplova M, Inamati GB, Lesnik EA, Owens SR, Ross BS, Prakash TP, Manoharan M. Egli M, et al. Among authors: ross bs. Biochemistry. 2005 Jun 28;44(25):9045-57. doi: 10.1021/bi050574m. Biochemistry. 2005. PMID: 15966728 Free article.

9

Process research on the preparation of DMT protected 2'-O-methoxyethylguanosine for oligonucleotide synthesis in therapeutic applications.

Taj SA, Narayanan S, Meenakshi SS, Sanghvi YS, Ross BS, Ravikumar VT. Taj SA, et al. Among authors: ross bs. Nucleosides Nucleotides Nucleic Acids. 2008 Sep;27(9):1024-33. doi: 10.1080/15257770802271748. Nucleosides Nucleotides Nucleic Acids. 2008. PMID: 18711665

10

An efficient and scalable synthesis of 2,6-diaminopurine riboside.

Ross BS, Springer RH, Ravikumar VT. Ross BS, et al. Nucleosides Nucleotides Nucleic Acids. 2008 Jan;27(1):67-9. doi: 10.1080/15257770701571990. Nucleosides Nucleotides Nucleic Acids. 2008. PMID: 18188771

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