Gamage SA - Search Results

1

Comparative biodistribution and metabolism of carbon-11-labeled N-[2-(dimethylamino)ethyl]acridine-4-carboxamide and DNA-intercalating analogues.

Osman S, Rowlinson-Busza G, Luthra SK, Aboagye EO, Brown GD, Brady F, Myers R, Gamage SA, Denny WA, Baguley BC, Price PM. Osman S, et al. Among authors: gamage sa. Cancer Res. 2001 Apr 1;61(7):2935-44. Cancer Res. 2001. PMID: 11306471

2

Structure-activity relationships for acridine-substituted analogues of the mixed topoisomerase I/II inhibitor N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.

Spicer JA, Gamage SA, Atwell GJ, Finlay GJ, Baguley BC, Denny WA. Spicer JA, et al. Among authors: gamage sa. J Med Chem. 1997 Jun 6;40(12):1919-29. doi: 10.1021/jm970004n. J Med Chem. 1997. PMID: 9191970

3

Dimeric analogues of non-cationic tricyclic aromatic carboxamides are a new class of cytotoxic agents.

Spicer JA, Gamage SA, Atwell GJ, Finlay GJ, Baguley BC, Denny WA. Spicer JA, et al. Among authors: gamage sa. Anticancer Drug Des. 1999 Jun;14(3):281-9. Anticancer Drug Des. 1999. PMID: 10500503

4

Structure-activity relationships for substituted bis(acridine-4-carboxamides): a new class of anticancer agents.

Gamage SA, Spicer JA, Atwell GJ, Finlay GJ, Baguley BC, Denny WA. Gamage SA, et al. J Med Chem. 1999 Jul 1;42(13):2383-93. doi: 10.1021/jm980687m. J Med Chem. 1999. PMID: 10395479

5

Bis(phenazine-1-carboxamides): structure-activity relationships for a new class of dual topoisomerase I/II-directed anticancer drugs.

Spicer JA, Gamage SA, Rewcastle GW, Finlay GJ, Bridewell DJ, Baguley BC, Denny WA. Spicer JA, et al. Among authors: gamage sa. J Med Chem. 2000 Apr 6;43(7):1350-8. doi: 10.1021/jm990423f. J Med Chem. 2000. PMID: 10753472

6

Dicationic bis(9-methylphenazine-1-carboxamides): relationships between biological activity and linker chain structure for a series of potent topoisomerase targeted anticancer drugs.

Gamage SA, Spicer JA, Finlay GJ, Stewart AJ, Charlton P, Baguley BC, Denny WA. Gamage SA, et al. J Med Chem. 2001 Apr 26;44(9):1407-15. doi: 10.1021/jm0003283. J Med Chem. 2001. PMID: 11311063

7

Structure-activity relationships for substituted 9-oxo-9,10-dihydroacridine-4-acetic acids: analogues of the colon tumour active agent xanthenone-4-acetic acid.

Gamage SA, Rewcastle GW, Atwell GJ, Baguley BC, Denny WA. Gamage SA, et al. Anticancer Drug Des. 1992 Oct;7(5):403-14. Anticancer Drug Des. 1992. PMID: 1388631

8

Structure-activity relationships of 9-anilinoacridines as inhibitors of human DNA topoisomerase II.

Figgitt DP, Denny WA, Gamage SA, Ralph RK. Figgitt DP, et al. Among authors: gamage sa. Anticancer Drug Des. 1994 Jun;9(3):199-208. Anticancer Drug Des. 1994. PMID: 8031452

9

Synthesis and in vitro evaluation of 9-anilino-3,6-diaminoacridines active against a multidrug-resistant strain of the malaria parasite Plasmodium falciparum.

Gamage SA, Tepsiri N, Wilairat P, Wojcik SJ, Figgitt DP, Ralph RK, Denny WA. Gamage SA, et al. J Med Chem. 1994 May 13;37(10):1486-94. doi: 10.1021/jm00036a014. J Med Chem. 1994. PMID: 8182707

10

Structure-activity relationships and modes of action of 9-anilinoacridines against chloroquine-resistant Plasmodium falciparum in vitro.

Chavalitshewinkoon P, Wilairat P, Gamage S, Denny W, Figgitt D, Ralph R. Chavalitshewinkoon P, et al. Antimicrob Agents Chemother. 1993 Mar;37(3):403-6. doi: 10.1128/AAC.37.3.403. Antimicrob Agents Chemother. 1993. PMID: 8384810 Free PMC article.

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