Sleight AJ - Search Results

1

5-HT(6) receptor antagonists: lead optimisation and biological evaluation of N-aryl and N-heteroaryl 4-amino-benzene sulfonamides.

Bös M, Sleight AJ, Godel T, Martin JR, Riemer C, Stadler H. Bös M, et al. Among authors: sleight aj. Eur J Med Chem. 2001 Feb;36(2):165-78. doi: 10.1016/s0223-5234(00)01209-5. Eur J Med Chem. 2001. PMID: 11311747

2

Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonists.

Hoffmann T, Bös M, Stadler H, Schnider P, Hunkeler W, Godel T, Galley G, Ballard TM, Higgins GA, Poli SM, Sleight AJ. Hoffmann T, et al. Among authors: sleight aj. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1362-5. doi: 10.1016/j.bmcl.2005.11.047. Epub 2005 Dec 5. Bioorg Med Chem Lett. 2006. PMID: 16332435

3

Novel agonists of 5HT2C receptors. Synthesis and biological evaluation of substituted 2-(indol-1-yl)-1-methylethylamines and 2-(indeno[1,2-b]pyrrol-1-yl)-1-methylethylamines. Improved therapeutics for obsessive compulsive disorder.

Bös M, Jenck F, Martin JR, Moreau JL, Sleight AJ, Wichmann J, Widmer U. Bös M, et al. Among authors: sleight aj. J Med Chem. 1997 Aug 15;40(17):2762-9. doi: 10.1021/jm970030l. J Med Chem. 1997. PMID: 9276022

4

Characterization of Ro 04-6790 and Ro 63-0563: potent and selective antagonists at human and rat 5-HT6 receptors.

Sleight AJ, Boess FG, Bös M, Levet-Trafit B, Riemer C, Bourson A. Sleight AJ, et al. Br J Pharmacol. 1998 Jun;124(3):556-62. doi: 10.1038/sj.bjp.0701851. Br J Pharmacol. 1998. PMID: 9647481 Free PMC article.

5

The 5-hydroxytryptamine6 receptor-selective radioligand [3H]Ro 63-0563 labels 5-hydroxytryptamine receptor binding sites in rat and porcine striatum.

Boess FG, Riemer C, Bös M, Bentley J, Bourson A, Sleight AJ. Boess FG, et al. Among authors: sleight aj. Mol Pharmacol. 1998 Sep;54(3):577-83. doi: 10.1124/mol.54.3.577. Mol Pharmacol. 1998. PMID: 9730917

6

Discovery of potent, balanced and orally active dual NK1/NK3 receptor ligands.

Peters JU, Hoffmann T, Schnider P, Stadler H, Koblet A, Alker A, Poli SM, Ballard TM, Spooren W, Steward L, Sleight AJ. Peters JU, et al. Among authors: sleight aj. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3405-8. doi: 10.1016/j.bmcl.2010.04.008. Epub 2010 Apr 9. Bioorg Med Chem Lett. 2010. PMID: 20430616

7

Involvement of 5-HT6 receptors in nigro-striatal function in rodents.

Bourson A, Boess FG, Bös M, Sleight AJ. Bourson A, et al. Among authors: sleight aj. Br J Pharmacol. 1998 Dec;125(7):1562-6. doi: 10.1038/sj.bjp.0702230. Br J Pharmacol. 1998. PMID: 9884085 Free PMC article.

8

O-methylasparvenone, a nitrogen-free serotonin antagonist.

Bös M, Canesso R, Inoue-Ohga N, Nakano A, Takehana Y, Sleight AJ. Bös M, et al. Among authors: sleight aj. Bioorg Med Chem. 1997 Dec;5(12):2165-71. doi: 10.1016/s0968-0896(97)00160-0. Bioorg Med Chem. 1997. PMID: 9459014

9

The putative 5-ht6 receptor: localization and function.

Sleight AJ, Boess FG, Bös M, Bourson A. Sleight AJ, et al. Ann N Y Acad Sci. 1998 Dec 15;861:91-6. doi: 10.1111/j.1749-6632.1998.tb10178.x. Ann N Y Acad Sci. 1998. PMID: 9928244 Review.

10

5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential.

Martin JR, Bös M, Jenck F, Moreau J, Mutel V, Sleight AJ, Wichmann J, Andrews JS, Berendsen HH, Broekkamp CL, Ruigt GS, Köhler C, Delft AM. Martin JR, et al. Among authors: sleight aj. J Pharmacol Exp Ther. 1998 Aug;286(2):913-24. J Pharmacol Exp Ther. 1998. PMID: 9694950

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