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Cooperative antitumor effect of mixed backbone oligonucleotides targeting protein kinase A in combination with cytotoxic drugs or biologic agents.
Tortora G, Caputo R, Damiano V, Bianco R, Pepe S, Pomatico G, Bianco AR, Jiang Z, Agrawal S, Ciardiello F. Tortora G, et al. Among authors: caputo r. Antisense Nucleic Acid Drug Dev. 1998 Apr;8(2):141-5. doi: 10.1089/oli.1.1998.8.141. Antisense Nucleic Acid Drug Dev. 1998. PMID: 9593054 Review. No abstract available.
Resistance to taxanes is induced by c-erbB-2 overexpression in human MCF-10A mammary epithelial cells and is blocked by combined treatment with an antisense oligonucleotide targeting type I protein kinase A.
Ciardiello F, Caputo R, Pomatico G, De Laurentiis M, De Placido S, Bianco AR, Tortora G. Ciardiello F, et al. Among authors: caputo r. Int J Cancer. 2000 Mar 1;85(5):710-5. doi: 10.1002/(sici)1097-0215(20000301)85:5<710::aid-ijc18>3.0.co;2-4. Int J Cancer. 2000. PMID: 10699953
Antiangiogenic and antitumor activity of anti-epidermal growth factor receptor C225 monoclonal antibody in combination with vascular endothelial growth factor antisense oligonucleotide in human GEO colon cancer cells.
Ciardiello F, Bianco R, Damiano V, Fontanini G, Caputo R, Pomatico G, De Placido S, Bianco AR, Mendelsohn J, Tortora G. Ciardiello F, et al. Among authors: caputo r. Clin Cancer Res. 2000 Sep;6(9):3739-47. Clin Cancer Res. 2000. PMID: 10999768
774 results